Reactome | SET2 [nucleoplasm]

SET2 [nucleoplasm]

Stable Identifier

R-SCE-1183215

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

WHSC1, P46995

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P46995

Gene Names

SET2

Reference Genes

BioGPS Gene:853271 SET2

ENSEMBL:YJL168C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YJL168C SET2

Monarch:853271 SET2

NCBI Gene:853271 SET2

SGD:YJL168C

Reference Transcript

RefSeq:NM_001181601.2 SET2

Other Identifiers

11170_at

1778840_at

853271

GO:0000785

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005829

GO:0006260

GO:0006310

GO:0006325

GO:0006338

GO:0006353

GO:0006354

GO:0006355

GO:0008150

GO:0008168

GO:0008213

GO:0008270

GO:0010452

GO:0016570

GO:0016571

GO:0016575

GO:0016740

GO:0018193

GO:0030174

GO:0030437

GO:0031399

GO:0032259

GO:0033043

GO:0034968

GO:0035066

GO:0042054

GO:0043167

GO:0043543

GO:0043934

GO:0045128

GO:0046975

GO:0048285

GO:0051052

GO:0051321

GO:0051726

GO:0060195

GO:0071441

GO:0140955

GO:1900049

GO:2000616

Participates

as a member of

WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Saccharomyces cerevisiae)

as an input of

WHSC1 binds DNA DSBs (Saccharomyces cerevisiae)

as a component of

DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

SET2 [nucleoplasm]

phospho-SET2 [nucleoplasm]

Inferred From

WHSC1, WHSC1L1 [nucleoplasm] (Homo sapiens)

WHSC1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_012367.2

IntEnz

2.1.1.359

PRO

P46995

PDB

7EA5, 2C5Z, 1E0N

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61830	13	HHT2 [nucleoplasm] (R-SCE-427369) HHT2 [nucleoplasm] (R-SCE-427504) HHT2 [nucleoplasm] (R-SCE-5250654) HHT2 [nucleoplasm] (R-SCE-427324) phospho-HHT2 [nucleoplasm] (R-SCE-5625878) phospho-HHT2 [nucleoplasm] (R-SCE-5625858) HHT2 [nucleoplasm] (R-SCE-5625800) phospho-HHT2 [nucleoplasm] (R-SCE-5625758) HHT2 [nucleoplasm] (R-SCE-5625747) HHT2 [nucleoplasm] (R-SCE-1214216) HHT2 [nucleoplasm] (R-SCE-212282) HHT2 [nucleoplasm] (R-SCE-212295) HHT2 [nucleoplasm] (R-SCE-1214206)	0.623	2
UniProt:P04050	6	phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm] (R-SCE-6810226) phospho-p-S5(CTD)-POLR2A [nucleoplasm] (R-SCE-77100) phospho-Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-SCE-6781855) phospho-p-3S-POLR2A [nucleoplasm] (R-SCE-6797701) phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-SCE-113420) POLR2A [nucleoplasm] (R-SCE-63502)	0.564	5
UniProt:P11484	17	HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	3
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2

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