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POLH [nucleoplasm]
Stable Identifier
R-SCE-110287
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
Synonyms
Q04049
Locations in the PathwayBrowser
Expand all
DNA Repair (Saccharomyces cerevisiae)
DNA Damage Bypass (Saccharomyces cerevisiae)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Saccharomyces cerevisiae)
Termination of translesion DNA synthesis (Saccharomyces cerevisiae)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Saccharomyces cerevisiae)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
DNA polymerase Y [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
DNA polymerase Y [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Saccharomyces cerevisiae)
DNA polymerase Y [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
DNA polymerase Y [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
Translesion Synthesis by POLH (Saccharomyces cerevisiae)
Elongation by POLH (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
Insertion of correct bases opposite the lesion by POLH (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Saccharomyces cerevisiae)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Saccharomyces cerevisiae)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
POLH [nucleoplasm] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:Q04049
Reference Genes
BioGPS Gene:852028
ENSEMBL:YDR419W
KEGG:sce:YDR419W
Monarch:852028
NCBI Gene:852028
SGD:YDR419W
UCSC:Q04049
Reference Transcript
RefSeq:NM_001180727.3
Other Identifiers
1777699_at
6071_at
852028
GO:0000278
GO:0003674
GO:0003677
GO:0003684
GO:0003887
GO:0005515
GO:0005575
GO:0005634
GO:0005657
GO:0005694
GO:0005737
GO:0005739
GO:0006260
GO:0006281
GO:0006974
GO:0007059
GO:0007064
GO:0008150
GO:0008270
GO:0009314
GO:0016740
GO:0016779
GO:0035861
GO:0042276
GO:0043167
GO:0043231
GO:0046872
GO:0048285
GO:0070987
GO:0071897
Participates
as a member of
DNA polymerase Y [nucleoplasm] (Saccharomyces cerevisiae)
as an output of
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Saccharomyces cerevisiae)
as an input of
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Saccharomyces cerevisiae)
as a component of
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Saccharomyces cerevisiae)
Inferred From
POLH [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_010707.3
ENSEMBL
YDR419W
,
YDR419W_mRNA
,
YDR419W
PRO
Q04049
PDB
5VTP
,
3OHB
,
3OHA
,
3MFH
,
2XGQ
,
2XGP
,
2R8J
,
2R8K
,
2WTF
,
1JIH
,
3MFI
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15873
5
POL30 [nucleoplasm]
(R-SCE-68439)
POL30 [nucleoplasm]
(R-SCE-5651986)
POL30 [nucleoplasm]
(R-SCE-5653768)
POL30 [nucleoplasm]
(R-SCE-8943000)
POL30 [nucleoplasm]
(R-SCE-4615861)
0.783
7
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