Reactome | RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-RNO-983062-7

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

class I MHC B73, F1LQF2

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Rattus norvegicus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Budding of COPII coated vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Capturing cargo and formation of prebudding complex (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Formation of peptide loading complex (PLC) (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Loading of antigenic peptides on to class I MHC (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Transport of MHC heterotrimer to ER exit site (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F1LQF2

Gene Names

RT1-S3

Reference Genes

BioGPS Gene:294228 RT1-S3

CTD Gene:294228 RT1-S3

ENSEMBL:ENSRNOG00000000777

ENSEMBL:ENSRNOG00000000777 RT1-S3

KEGG Gene (Rattus norvegicus):294228 RT1-S3

Monarch:294228 RT1-S3

NCBI Gene:294228 RT1-S3

Reference Transcript

Other Identifiers

10827809

1371123_x_at

1388212_a_at

1388213_a_at

17752507

294228

5726670

5743242

5827513

5887294

5911921

6072756

6266845

6430515

6482876

6538983

6725937

6743955

AF029240_at

A_44_P128151

GO:0001815

GO:0001916

GO:0002250

GO:0002376

GO:0002476

GO:0002477

GO:0002489

GO:0002519

GO:0002715

GO:0002717

GO:0002729

GO:0003674

GO:0005102

GO:0005575

GO:0005576

GO:0005615

GO:0005886

GO:0006810

GO:0006950

GO:0007155

GO:0008150

GO:0008283

GO:0009897

GO:0009986

GO:0015031

GO:0016020

GO:0016021

GO:0019731

GO:0030881

GO:0032398

GO:0032736

GO:0032753

GO:0032759

GO:0032760

GO:0032819

GO:0032991

GO:0036037

GO:0042270

GO:0042288

GO:0042605

GO:0042608

GO:0042612

GO:0045953

GO:0045954

GO:0046703

GO:0048839

GO:0048856

GO:0050830

GO:0051024

GO:2000566

GO:2001187

rc_AI235890_s_at

Participant Of

hasMember

Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane]

Other forms of this molecule

RT1-S3 [azurophil granule membrane]

RT1-S3 [phagocytic vesicle membrane]

RT1-S3 [recycling endosome membrane]

RT1-S3 [early endosome membrane]

RT1-S3 [plasma membrane]

RT1-S3 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-S3 [Golgi membrane]

RT1-S3 [plasma membrane]

RT1-S3 [ER to Golgi transport vesicle membrane]

RT1-S3 [early endosome membrane]

Inferred From

class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_006255979.1, NP_001008886.2

Ensembl

ENSRNOT00000001036, ENSRNOG00000000777, ENSRNOP00000001036

RGD

735037

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