Reactome | RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-RNO-983062-22

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

class I MHC B73, Q95II0

Locations in the PathwayBrowser

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Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Rattus norvegicus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Budding of COPII coated vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Capturing cargo and formation of prebudding complex (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Formation of peptide loading complex (PLC) (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Loading of antigenic peptides on to class I MHC (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Transport of MHC heterotrimer to ER exit site (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q95II0

Gene Names

RT1-CE5

Reference Genes

BioGPS Gene:309607 RT1-CE5

CTD Gene:309607 RT1-CE5

ENSEMBL:ENSRNOG00000000723

ENSEMBL:ENSRNOG00000000723 RT1-CE5

KEGG Gene (Rattus norvegicus):309607 RT1-CE5

Monarch:309607 RT1-CE5

NCBI Gene:309607 RT1-CE5

Reference Transcript

Other Identifiers

10831099

1370972_x_at

1371209_at

1371210_s_at

1388255_x_at

17756281

309607

5681011

5694781

5735626

5749495

5817745

5820637

5875968

5943543

5944010

6005738

6026371

6073732

6167766

6169067

6343495

6379175

6390118

6396165

6423532

6495343

6545163

6623790

6639078

6663729

A_44_P172850

A_64_P090474

A_64_P090475

GO:0000139

GO:0001916

GO:0002376

GO:0002476

GO:0002477

GO:0002725

GO:0002728

GO:0002729

GO:0003674

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005783

GO:0005794

GO:0005886

GO:0006810

GO:0006950

GO:0006955

GO:0008150

GO:0008219

GO:0009897

GO:0009986

GO:0016020

GO:0016021

GO:0016192

GO:0019882

GO:0030881

GO:0031410

GO:0031901

GO:0032398

GO:0032991

GO:0042605

GO:0043226

GO:0043322

GO:0043323

GO:0045953

GO:0046978

GO:0046979

GO:0071889

GO:1901215

ILMN_1376923

M24324_f_at

PH_rn_0024044

rc_AA858651_f_at

rc_AI103500_f_at

Participant Of

hasMember

Homologues of class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane]

Other forms of this molecule

RT1-CE5 [azurophil granule membrane]

RT1-CE5 [phagocytic vesicle membrane]

RT1-CE5 [recycling endosome membrane]

RT1-CE5 [early endosome membrane]

RT1-CE5 [plasma membrane]

RT1-CE5 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-CE5 [Golgi membrane]

RT1-CE5 [plasma membrane]

RT1-CE5 [ER to Golgi transport vesicle membrane]

RT1-CE5 [early endosome membrane]

Inferred From

class I MHC B73 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001008843.1, NP_001029158.1

Ensembl

ENSRNOP00000057699, ENSRNOT00000060980, ENSRNOG00000000723

RGD

1595868

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