Reactome | RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-RNO-983044-14

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor, Q6MFZ8

Locations in the PathwayBrowser

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Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Rattus norvegicus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Budding of COPII coated vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Formation of peptide loading complex (PLC) (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Loading of antigenic peptides on to class I MHC (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Transport of MHC heterotrimer to ER exit site (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q6MFZ8

Gene Names

RT1-N2

Reference Genes

BioGPS Gene:360323 RT1-N2

CTD Gene:360323 RT1-N2

ENSEMBL:ENSRNOG00000029386

KEGG Gene (Rattus norvegicus):360323 RT1-N2

Monarch:360323 RT1-N2

NCBI Gene:360323 RT1-N2

UCSC:Q6MFZ8 RT1-N2

Reference Transcript

Other Identifiers

10827782

1387839_at

17752474

360323

5710613

5826119

5841468

5863607

6000403

6164956

6193811

6204723

6231624

6320278

6325929

6339954

6375369

6523100

AA848333_at

A_64_P057281

GO:0002376

GO:0002476

GO:0005576

GO:0005615

GO:0005886

GO:0009897

GO:0016020

GO:0016021

PH_rn_0013023

rc_AA818887_at

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)

Other forms of this molecule

RT1-N2 [secretory granule membrane]

RT1-N2 [azurophil granule membrane]

RT1-N2 [ER to Golgi transport vesicle membrane]

RT1-N2 [Golgi membrane]

RT1-N2 [phagocytic vesicle membrane]

RT1-N2 [recycling endosome membrane]

RT1-N2 [plasma membrane]

RT1-N2 [early endosome membrane]

RT1-N2 [integral component of lumenal side of endoplasmic reticulum membrane]

Inferred From

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001008854.1, XP_006256000.1

Ensembl

ENSRNOP00000049883, ENSRNOG00000029386, ENSRNOT00000050159

RGD

1595850

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