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KMT2A(2719-3969) [nucleoplasm]
Stable Identifier
R-RNO-9818593
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
F1M0L3
Locations in the PathwayBrowser
Expand all
Chromatin organization (Rattus norvegicus)
Chromatin modifying enzymes (Rattus norvegicus)
PKMTs methylate histone lysines (Rattus norvegicus)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)
Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Rattus norvegicus)
SETD3, SETD7, WHSC1L1, Core MLL complex [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)
WHSC1L1, Core MLL complex, SMYD3, SETD3 [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
Epigenetic regulation of gene expression (Rattus norvegicus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Rattus norvegicus)
Formation of WDR5-containing histone-modifying complexes (Rattus norvegicus)
AKAP8L binds MLL1 complex (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:AKAP8L [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
Cleaved KMT2A dimers translocate to the nucleus (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
Formation of the MLL1 complex (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
HCFC1, HCFC2 bind the MLL1:MEN1 complex (Rattus norvegicus)
MLL1 complex,MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex,MLL1 complex:MEN1:HCFC1,HCFC2 [nucleoplasm] (Rattus norvegicus)
MLL1 complex:HCFC1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:HCFC2 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1:HCFC1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1:HCFC2 [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MEN1 binds MLL1 complex (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
PSIP1 binds MLL1 and MEN1 (Rattus norvegicus)
MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1:PSIP1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex:MEN1 [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional regulation by RUNX1 (Rattus norvegicus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Rattus norvegicus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Rattus norvegicus)
Core MLL complex [nucleoplasm] (Rattus norvegicus)
MLL1 complex [nucleoplasm] (Rattus norvegicus)
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
KMT2A(2719-3969) [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:F1M0L3
Reference Genes
ENSEMBL:ENSRNOG00000015133
UCSC:F1M0L3
Other Identifiers
10916880
1375793_at
1378210_at
1378211_s_at
1393752_at
1395419_at
1398619_at
17851886
315606
5637814
5641093
5664330
5681398
5709313
5721054
5744682
5769609
5784482
5813848
5888913
5898230
5899215
5933400
5937401
5939956
5944094
5995246
6012862
6024924
6044794
6085456
6175667
6188732
6205932
6206884
6212864
6222212
6231457
6237979
6255774
6256823
6264980
6270810
6283792
6350480
6370526
6397823
6402934
6403284
6422583
6427047
6449027
6449534
6458281
6481197
6490892
6497453
6552207
6555870
6559911
6594848
6622447
6648449
6705134
6712772
A_43_P18570
A_44_P295522
A_44_P607813
A_44_P882219
A_64_P105605
GE1123123
GE1244162
GE1290378
GO:0002376
GO:0003677
GO:0003682
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006306
GO:0006325
GO:0006351
GO:0006355
GO:0008270
GO:0008542
GO:0009416
GO:0009791
GO:0009952
GO:0010468
GO:0016740
GO:0023052
GO:0030154
GO:0032922
GO:0035097
GO:0035162
GO:0035640
GO:0036211
GO:0042393
GO:0042800
GO:0042802
GO:0042803
GO:0043226
GO:0045064
GO:0045322
GO:0045815
GO:0045893
GO:0045944
GO:0048144
GO:0048147
GO:0048172
GO:0048536
GO:0048856
GO:0048873
GO:0050877
GO:0050890
GO:0051568
GO:0060216
GO:0065003
GO:0070577
GO:0071339
GO:0090310
GO:0106363
GO:0140096
GO:0140999
ILMN_1352768
PH_rn_0010588
rc_AI060250_s_at
rc_AI146227_i_at
Participates
as a component of
KMT2A dimer [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
KMT2A [cytosol]
KMT2A(2719-3969) [cytosol]
KMT2A(1-2718) [cytosol]
KMT2A [nucleoplasm]
KMT2A(1-2718) [nucleoplasm]
Inferred From
KMT2A(2719-3969) [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSRNOT00000020573
,
ENSRNOP00000020573
RGD
1586165
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