Reactome | N4bp1 [cytosol]

N4bp1 [cytosol]

Stable Identifier

R-RNO-9757940

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

N4BP1(1-424), D3ZT79

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Signaling by Interleukins (Rattus norvegicus)
    - Interleukin-1 family signaling (Rattus norvegicus)
      - Interleukin-1 signaling (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
- Innate Immune System (Rattus norvegicus)
  - Toll-like Receptor Cascades (Rattus norvegicus)
    - Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
      - MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
    - Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
      - Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
      - Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
    - Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
      - TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
    - Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
      - MyD88-independent TLR4 cascade (Rattus norvegicus)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
    - Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
      - MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
      - MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)
    - Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
      - MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
        
        Regulation of NF-kappa B signaling (Rattus norvegicus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)
        
        N4bp1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZT79

Gene Names

N4bp1

Reference Genes

BioGPS Gene:291921 N4bp1

ENSEMBL:ENSRNOG00000015121

ENSEMBL:ENSRNOG00000015121.9 N4bp1

KEGG Gene (Rattus norvegicus):291921 N4bp1

Monarch:291921 N4bp1

NCBI Gene:291921 N4bp1

Reference Transcript

RefSeq:NM_001305181.1 N4bp1

Other Identifiers

10806365

1376205_at

1390859_at

1391222_at

17728370

291921

5625037

5759143

5875513

5949242

5952760

6013543

6028114

6100770

6164925

6263011

6297261

6313061

6348453

6349087

6436699

A_44_P1044517

A_44_P991773

A_64_P007030

GE1198008

GE15748

GO:0001818

GO:0002376

GO:0003723

GO:0003729

GO:0003824

GO:0004540

GO:0005634

GO:0005654

GO:0005730

GO:0005829

GO:0016605

GO:0016787

GO:0030163

GO:0031397

GO:0032435

GO:0034644

GO:0036211

GO:0043130

GO:0043226

GO:0045071

GO:0045088

GO:0098542

GO:0140098

ILMN_1356291

PH_rn_0018348

rc_AI008339_at

Participates

as an output of

CASP8 cleaves N4BP1 at D424, D490 (Rattus norvegicus)

Other forms of this molecule

N4bp1 [cytosol]

Inferred From

N4BP1(1-424), N4BP1(1-490) [cytosol] (Homo sapiens)

N4BP1(1-424) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001292110.1

Ensembl

ENSRNOP00000042818, ENSRNOT00000049285, ENSRNOG00000015121

RGD

1305179

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