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MyrG2-PalmC3-LYN [endocytic vesicle membrane]
Stable Identifier
R-RNO-9705728
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endocytic vesicle membrane
Synonyms
Q07014
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by CSF3 (G-CSF) (Rattus norvegicus)
Inactivation of CSF3 (G-CSF) signaling (Rattus norvegicus)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Rattus norvegicus)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:K48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
MyrG2-PalmC3-LYN [endocytic vesicle membrane] (Rattus norvegicus)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
MyrG2-PalmC3-LYN [endocytic vesicle membrane] (Rattus norvegicus)
SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Rattus norvegicus)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:K48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
MyrG2-PalmC3-LYN [endocytic vesicle membrane] (Rattus norvegicus)
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
MyrG2-PalmC3-LYN [endocytic vesicle membrane] (Rattus norvegicus)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Rattus norvegicus)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
CSF3 dimer:p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
MyrG2-PalmC3-LYN [endocytic vesicle membrane] (Rattus norvegicus)
p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
MyrG2-PalmC3-LYN [endocytic vesicle membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q07014 Lyn
Gene Names
Lyn
Chain
initiator methionine:, chain:2-512
Reference Genes
BioGPS Gene:81515 Lyn
KEGG:rno:81515 Lyn
Monarch:81515 Lyn
NCBI Gene:81515 Lyn
UCSC:Q07014 Lyn
Reference Transcript
RefSeq:XM_006237834.3 Lyn
RefSeq:NM_030857.2 Lyn
RefSeq:NM_001111098.1 Lyn
Other Identifiers
10867461
1368679_a_at
1382346_at
1387277_at
17797097
5639378
5671198
5754967
5768717
5801431
5844063
5961595
6103285
6132399
6165179
6168291
6168366
6188997
6439622
6474028
6481820
6526236
6564238
6665033
6693681
81515
A_44_P273821
A_44_P316239
A_64_P048980
GE16636
GO:0000077
GO:0001782
GO:0001817
GO:0001933
GO:0001934
GO:0002244
GO:0002376
GO:0002431
GO:0002513
GO:0002576
GO:0002762
GO:0002768
GO:0002774
GO:0002902
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005794
GO:0005886
GO:0006468
GO:0006954
GO:0006974
GO:0007155
GO:0007169
GO:0008284
GO:0008285
GO:0009725
GO:0009898
GO:0009986
GO:0010976
GO:0012501
GO:0016192
GO:0016740
GO:0017124
GO:0023052
GO:0030097
GO:0030154
GO:0030218
GO:0030222
GO:0030335
GO:0030889
GO:0031175
GO:0031663
GO:0032991
GO:0033003
GO:0033628
GO:0034136
GO:0034142
GO:0034144
GO:0035556
GO:0036211
GO:0038043
GO:0038159
GO:0042060
GO:0042531
GO:0043226
GO:0043231
GO:0043304
GO:0043410
GO:0044325
GO:0044877
GO:0045121
GO:0045646
GO:0046875
GO:0048471
GO:0048856
GO:0048870
GO:0050727
GO:0050853
GO:0050855
GO:0051279
GO:0055065
GO:0055085
GO:0070372
GO:0070373
GO:0070667
GO:0070668
GO:0071300
GO:0090025
GO:0090330
GO:0097028
GO:0097110
GO:0098542
GO:0140031
GO:0140096
GO:0141038
GO:1902532
GO:2000670
ILMN_1372831
L14782_s_at
L14951_at
PH_rn_0003029
rc_AA946044_s_at
rc_AI012049_at
Participates
as a component of
K48polyUb-K655, p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
p-4Y-CSF3R:LYN:p-Y-JAK1 [endocytic vesicle membrane] (Rattus norvegicus)
Other forms of this molecule
MyrG2-PalmC3-LYN [lysosomal membrane]
LYN [plasma membrane]
phospho-p-Y397-LYN [cytosol]
phospho-p-Y397-LYN [plasma membrane]
MyrG2-PalmC3-LYN [plasma membrane]
Lyn [cytosol]
Inferred From
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
(Homo sapiens)
Modified Residues
Name
N-myristoylglycine at 2 (in Homo sapiens)
Coordinate
2
PsiMod Name
N-myristoylglycine [MOD:00068]
PsiMod Definition
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
Name
S-palmitoyl-L-cysteine at 3 (in Homo sapiens)
Coordinate
3
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Cross References
RefSeq
NP_001104568.1
,
XP_006237896.1
,
NP_110484.1
ZINC - Metabolites
LYN_RAT
ZINC - World Drugs
LYN_RAT
ENSEMBL
ENSRNOT00000011130
,
ENSRNOG00000008180
,
ENSRNOP00000011130
ZINC - Substances
LYN_RAT
ZINC - Biogenic
LYN_RAT
ZINC target
Q07014
PRO
Q07014
RGD
621017
ZINC - Predictions - Purchasable
LYN_RAT
HMDB Protein
HMDBP13825
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