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Gsdme [cytosol]
Stable Identifier
R-RNO-9647689
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
GSDME(1-270), F1MAG0
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Regulation of TLR by endogenous ligand (Rattus norvegicus)
HMGB1 release from cells (Rattus norvegicus)
GSDME oligomer:PIP [plasma membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Intrinsic Pathway for Apoptosis (Rattus norvegicus)
Apoptotic factor-mediated response (Rattus norvegicus)
Release of apoptotic factors from the mitochondria (Rattus norvegicus)
Release of Cytochrome c from mitochondria (Rattus norvegicus)
GSDME:cardiolipin [mitochondrial outer membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
Pyroptosis (Rattus norvegicus)
CASP3 cleaves GSDME (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
GSDME (1-270) binds PIPs (Rattus norvegicus)
GSDME (1-270):PIPs [plasma membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
GSDME (1-270) binds cardiolipin (Rattus norvegicus)
GSDME:cardiolipin [mitochondrial outer membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
GSDME oligomerizes (Rattus norvegicus)
GSDME (1-270):PIPs [plasma membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
GSDME oligomer:PIP [plasma membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
GZMB cleaves GSDME (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
HMGB1 release from cells (Rattus norvegicus)
GSDME oligomer:PIP [plasma membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
Release of Cytochrome c from mitochondria (Rattus norvegicus)
GSDME:cardiolipin [mitochondrial outer membrane] (Rattus norvegicus)
Gsdme [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:F1MAG0
Gene Names
Gsdme
Reference Genes
ENSEMBL:ENSRNOG00000009970
Other Identifiers
10862464
17791270
353316
5669418
5819513
5840633
5957452
6054626
6125340
6202628
6256177
6282112
6583344
A_44_P423813
GE1160969
GO:0003674
GO:0005546
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0007165
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0008289
GO:0012501
GO:0016020
GO:0030154
GO:0043167
GO:0043410
GO:0048856
GO:0060113
GO:0070265
GO:0070269
GO:0071356
GO:0098586
GO:1901612
GO:2001244
ILMN_1358020
ILMN_1371764
PH_rn_0016443
Participates
as an input of
GSDME (1-270) binds cardiolipin (Rattus norvegicus)
GSDME (1-270) binds PIPs (Rattus norvegicus)
GSDME oligomerizes (Rattus norvegicus)
as an output of
GZMB cleaves GSDME (Rattus norvegicus)
CASP3 cleaves GSDME (Rattus norvegicus)
as a component of
GSDME (1-270):PIPs [plasma membrane] (Rattus norvegicus)
GSDME:cardiolipin [mitochondrial outer membrane] (Rattus norvegicus)
GSDME oligomer:PIP [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
Gsdme [cytosol]
Gsdme [cytosol]
Inferred From
GSDME(1-270) [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSRNOT00000013264
,
ENSRNOG00000009970
,
ENSRNOP00000013264
RGD
727871
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