Expression of Ddit3

Stable Identifier
R-RNO-9635847
Type
Reaction [omitted]
Species
Rattus norvegicus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Ddit3
The Ddit3 (CHOP) gene is transcribed to yield mRNA and the mRNA is translated to yield protein (Marten et al. 1994, Fawcett et al. 1999). Expression of Ddit3 is enhanced by Atf4, which binds a composite CEBP-ATF element in the promoter of the Ddit3 (CHOP) gene (Fawcett et al. 1999).
Literature References
Participants
Input
Output
This event is regulated
Positively by
Regulator
Atf4:Ddit3 gene [nucleoplasm] (Rattus norvegicus)
Orthologous Events
Transcription of DDIT3 (CHOP, GADD153) in response to amino acid deficiency (Homo sapiens)
Transcription of DDIT3 (CHOP, GADD153) in response to heme deficiency (Homo sapiens)
Expression of DDIT3 (CHOP, GADD153) in response to unfolded protein (Homo sapiens)
Authored
May, B  (2019-02-06)
Reviewed
Staschke, KA  (2019-11-20)
Chen, JJ  (2019-10-22)
Bruhat, A  (2019-09-15)
Created
May, B  (2019-02-09)
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