rNF-Y and Crebbp/Ep300 constitutively bind Bim gene promoter

Stable Identifier
R-RNO-9622571
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
rNF-Y and Crebbp/Ep300 constitutively bind Bim gene promoter

In rat neurons, endogenous NF-Y transcription factor complex (composed of Nfya, Nfyb and Nfyc) and endogenous histone acetyltransferases Ep300 (p300) and/or Crebbp (Cbp) constitutively bind to evolutionarily conserved sites in the promoter of the rat Bcl2l11 (Bim) gene (Hughes et al. 2011).

Literature References
PubMed ID Title Journal Year
21164521 NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons

Hughes, R, Kristiansen, M, Lassot, I, Desagher, S, Mantovani, R, Ham, J

Cell Death Differ. 2011
Participants
Orthologous Events
Authored
Reviewed
Created
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