Rps6ka1 autophosphorylates

Stable Identifier
R-RNO-9620003
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Rps6ka1 autophosphorylates
Upon phosphorylation by recombinant human MAPK1 (ERK2), recombinant rat Rps6ka1 autophosphorylates on serine residue S380 in the linker region and threonine residue T732 at the C-terminus (Dalby et al. 1998).
Literature References
PubMed ID Title Journal Year
9430688 Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

Cohen, P, Morrice, N, Caudwell, FB, Avruch, J, Dalby, KN

J. Biol. Chem. 1998
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of p-T359,S363,T573-Rps6ka1 [cytosol]

Physical Entity
p-T359,S363,T573-Rps6ka1 [cytosol] (Rattus norvegicus)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
RSKs autophosphorylate (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-10)
Reviewed
Hansen, KB  (2018-11-02)
Yi, F  (2018-11-02)
Created
Orlic-Milacic, M  (2018-09-19)
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