Reactome | GRIN2B [endoplasmic reticulum membrane]

GRIN2B [endoplasmic reticulum membrane]

Stable Identifier

R-RNO-9609765

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

endoplasmic reticulum membrane

Synonyms

Q00960

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q00960 Grin2b

Gene Names

Grin2b

Chain

signal peptide:1-26, chain:27-1482

Reference Genes

BioGPS Gene:24410 Grin2b

KEGG:rno:24410 Grin2b

Monarch:24410 Grin2b

NCBI Entrez Gene:24410 Grin2b

UCSC:Q00960 Grin2b

Reference Transcript

RefSeq:NM_012574.1 Grin2b

Participates

as an input of

Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Rattus norvegicus)

as a component of

Other forms of this molecule

GRIN2B [plasma membrane]

Grin2b [plasma membrane]

p-Y-Grin2b [plasma membrane]

Grin2b [endoplasmic reticulum membrane]

p-Y1472-Grin2b [plasma membrane]

phospho-p-Y1252,Y1336,Y1474-GRIN2B [plasma membrane]

Inferred From

GRIN2B [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_036706.1

ZINC - Investigational

NMDE2_RAT

ZINC - World Drugs

NMDE2_RAT

ZINC - Substances

NMDE2_RAT

ZINC - Biogenic

NMDE2_RAT

ZINC target

Q00960

PRO

Q00960

GlyGen

Q00960

RGD

2738

ZINC - Predictions - Purchasable

NMDE2_RAT

PDB

7TER, 5FXJ, 7TEQ, 5FXK, 8XLK, 7SAA, 7SAC, 8VUY, 6E7V, 9ARE, 6E7T, 8VVH, 7TE6, 7TEE, 9ARI, 6E7X, 6WHX, 6WHR, 6E7U, 6WI1, 6E7S, 3QEM, 6WHV, 9JNN, 6WHT, 5FXH, 5B3J, 3QEL, 7TET, 5FXI, 7TES, 8G18, 3JPY, 6CNA, 7SAB, 7SAD, 7TEB, 6E7W, 7TE9, 9ARG, 6WHW, 5TPZ, 6WI0, 6E7R, 9ARH, 9ARF, 4PE5, 6WHU, 6WHS, 6WHY, 5FXG, 3JPW

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31016 Dlg4	3	Dlg4 [plasma membrane] (R-RNO-9612601) Dlg4 [cytosol] (R-RNO-6794248) Dlg4 [endocytic vesicle membrane] (R-RNO-416847)	0.915	11
UniProt:P35439 Grin1	2	Grin1 [plasma membrane] (R-RNO-9610826) Grin1 [endoplasmic reticulum membrane] (R-RNO-9609841)	0.866	13
UniProt:A0A1L8F5J9-8 GRIN1			0.74	6
UniProt:P11798 Camk2a	6	phospho-p-T286-CAMK2A [plasma membrane] (R-MMU-432796) p-T286-Camk2a [nucleoplasm] (R-MMU-9608160) phospho-p-T286-CAMK2A [endocytic vesicle membrane] (R-MMU-416999) phospho-p-T286,T305,T306-CAMK2A [cytosol] (R-MMU-4332334) CAMK2A [cytosol] (R-MMU-4332329) phospho-p-T286-CAMK2A [cytosol] (R-MMU-445368)	0.704	4
UniProt:Q62936	2	Dlg3 [cytosol] (R-RNO-6794232) Dlg3 [plasma membrane] (R-RNO-443609)	0.704	6
UniProt:P11275 Camk2a	6	phospho-p-T286-CAMK2A [plasma membrane] (R-RNO-432796) phospho-p-T286-CAMK2A [nucleoplasm] (R-RNO-444797) phospho-p-T286-CAMK2A [endocytic vesicle membrane] (R-RNO-416999) phospho-p-T286,T305,T306-CAMK2A [cytosol] (R-RNO-4332334) Camk2a [cytosol] (R-RNO-9611390) p-T286-Camk2a [cytosol] (R-RNO-9618632)	0.589	2
UniProt:Q9Z252 Lin7b	1	Lin7b [plasma membrane] (R-RNO-6794272)	0.576	5
UniProt:Q63ZW7 INADL			0.508	4

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