Reactome | GRIN2C [endoplasmic reticulum membrane]

GRIN2C [endoplasmic reticulum membrane]

Stable Identifier

R-RNO-9609761

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

endoplasmic reticulum membrane

Synonyms

Q00961

Locations in the PathwayBrowser

Expand all

Neuronal System (Rattus norvegicus)

- Transmission across Chemical Synapses (Rattus norvegicus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
    - Activation of NMDA receptors and postsynaptic events (Rattus norvegicus)
      - Assembly and cell surface presentation of NMDA receptors (Rattus norvegicus)
        
        GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Rattus norvegicus)
        
        GRIN1:GRIN2A,C,D di-heteromers, GRIN1:GRIN2 tri-heteromers [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        GRIN2C [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        GRIN1:GRIN2C di-heterotetramer [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        GRIN2C [endoplasmic reticulum membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q00961 Grin2c

Gene Names

Grin2c

Chain

signal peptide:1-19, chain:20-1237

Reference Genes

BioGPS Gene:24411 Grin2c

KEGG Gene (Rattus norvegicus):24411 Grin2c

Monarch:24411 Grin2c

NCBI Gene:24411 Grin2c

Reference Transcript

Participates

as a component of

Other forms of this molecule

Grin2c [endoplasmic reticulum membrane]

p-Y-Grin2c [plasma membrane]

Grin2c [plasma membrane]

GRIN2C [plasma membrane]

Inferred From

GRIN2C [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

ZINC - Investigational

NMDE3_RAT

RefSeq

XP_006247769.1, XP_017452479.1, XP_017452481.1, NP_036707.3, XP_017452477.1, XP_006247771.1, XP_017452480.1, XP_017452476.1, XP_017452478.1, XP_017452475.1

ZINC - World Drugs

NMDE3_RAT

ZINC - FDA approved

NMDE3_RAT

ZINC - Substances

NMDE3_RAT

ZINC - Biogenic

NMDE3_RAT

ZINC target

Q00961

PRO

Q00961

RGD

2739

ZINC - Predictions - Purchasable

NMDE3_RAT

PDB

8HDK, 7YFI, 7YFG, 7YFH

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O88382 MAGI2			0.553	2
UniProt:P31016 Dlg4	3	Dlg4 [cytosol] (R-RNO-6794248) Dlg4 [endocytic vesicle membrane] (R-RNO-416847) Dlg4 [plasma membrane] (R-RNO-9612601)	0.553	2
UniProt:Q63ZW7 INADL			0.508	2

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