Ghrelin is a 27 or 28 residue long peptide that is the ligand of Growth hormone secretagogue receptor type 1 (GHSR). O-octanoylation or O-decanoylation is essential for ghrelin activity. GHSR activation induces the release of growth hormone from the pituitary. It has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Kojima, M, Hosoda, H, Date, Y, Nakazato, M, Matsuo, H, Kangawa, K
Smith, RG, Leonard, R, Bailey, AR, Palyha, O, Feighner, S, Tan, C, McKee, KK, Pong, SS, Griffin, P, Howard, A
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