Reactome | Tn antigens [Golgi lumen]

Tn antigens [Golgi lumen]

Stable Identifier

R-RNO-913659

Type

Set [DefinedSet]

Species

Rattus norvegicus

Compartment

Golgi lumen

Synonyms

N-acetyl-D-galactosaminyl-mucins

Locations in the PathwayBrowser

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Participants

members

Participates

as an input of

Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Rattus norvegicus)
Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Rattus norvegicus)
Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Rattus norvegicus)
Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Rattus norvegicus)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Rattus norvegicus)
C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Rattus norvegicus)
ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Rattus norvegicus)

as an output of

GALNTs transfer GalNAc to Mucins to form Tn antigens (Rattus norvegicus)

Inferred From

Tn antigens [Golgi lumen] (Homo sapiens)

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