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IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]
Stable Identifier
R-RNO-913412
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-2 family signaling (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
Phosphorylated SHC recruits GRB2:SOS1 (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
RAS GEFs [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane]
(Rattus norvegicus)
phospho-Shc1 [cytosol]
(Rattus norvegicus)
Participates
as a member of
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Rattus norvegicus)
Inferred From
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane]
(Homo sapiens)
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