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MyrG,p-Y420-Fyn [plasma membrane]
Stable Identifier
R-RNO-9032564
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
Netrin-1 signaling (Rattus norvegicus)
DCC mediated attractive signaling (Rattus norvegicus)
Activation of Cdc42 (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
Activation of Rac1 (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
DCC interacting NCK-1 (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
Phosphorylation of DCC by Fyn (Rattus norvegicus)
NTN1:DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
RhoGTPase GEF's recruited to DCC (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Rattus norvegicus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ERBB2 (Rattus norvegicus)
SRC family kinases phosphorylate ERBB2 (Rattus norvegicus)
p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK2 (TRKB) (Rattus norvegicus)
Activated NTRK2 signals through FYN (Rattus norvegicus)
NTRK2 activates RAC1 (Rattus norvegicus)
DOCK3 activates RAC1 (Rattus norvegicus)
BDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1:DOCK3 [plasma membrane] (Rattus norvegicus)
BDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1 [plasma membrane] (Rattus norvegicus)
MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q62844 Fyn
Gene Names
Fyn
Chain
initiator methionine:, chain:2-537
Reference Genes
BioGPS Gene:25150 Fyn
ENSEMBL:ENSRNOG00000000596.7 Fyn
ENSEMBL:ENSRNOG00055000725 Fyn
ENSEMBL:ENSRNOG00060007389 Fyn
ENSEMBL:ENSRNOG00065008840 Fyn
KEGG Gene (Rattus norvegicus):25150 Fyn
Monarch:25150 Fyn
NCBI Gene:25150 Fyn
UCSC:Q62844 Fyn
Reference Transcript
RefSeq:NM_012755.1 Fyn
Other Identifiers
10830382
1369103_at
17755483
25150
5680480
5692753
5720837
5767200
5772442
5893545
5915174
5988447
6008002
6017183
6093145
6185660
6217688
6335724
6594300
6621427
6625403
A_44_P149087
GE1218115
GO:0003824
GO:0004672
GO:0004713
GO:0005515
GO:0005524
GO:0006468
GO:0016740
GO:0036211
GO:0140096
ILMN_1362937
rc_AI009191_at
Participates
as a component of
Bdnf:p-5Y-Ntrk2 homodimer:MyrG,p-Y420-Fyn [plasma membrane] (Rattus norvegicus)
BDNF:p-5Y-NTRK2 homodimer:MyrG,p-Y420-FYN-1 [plasma membrane] (Rattus norvegicus)
as a member of
MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Rattus norvegicus)
as a candidate of
p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
MyrG-Fyn [plasma membrane]
phospho-p-S21,Y420-FYN [cytosol]
phospho-p-Y420-FYN [cytosol]
Fyn [cytosol]
Inferred From
MyrG-p-Y420-FYN-1 [plasma membrane]
(Homo sapiens)
MyrG-p-Y420-FYN [plasma membrane]
(Homo sapiens)
Modified Residues
Name
N-myristoylglycine at 2
Coordinate
2
PsiMod Name
N-myristoylglycine [MOD:00068]
PsiMod Definition
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
Name
O4'-phospho-L-tyrosine at 420
Coordinate
420
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_036887.1
Ensembl
ENSRNOP00000000733
,
ENSRNOG00000000596
,
ENSRNOT00000000733
PRO
Q62844
RGD
2641
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