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CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm]
Stable Identifier
R-RNO-8948131
Type
Set [CandidateSet]
Species
Rattus norvegicus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle Checkpoints (Rattus norvegicus)
G1/S DNA Damage Checkpoints (Rattus norvegicus)
p53-Dependent G1/S DNA damage checkpoint (Rattus norvegicus)
p53-Dependent G1 DNA Damage Response (Rattus norvegicus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
Mitotic G1 phase and G1/S transition (Rattus norvegicus)
G1 Phase (Rattus norvegicus)
Cyclin D associated events in G1 (Rattus norvegicus)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Rattus norvegicus)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Rattus norvegicus)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Rattus norvegicus)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
G1/S Transition (Rattus norvegicus)
Cyclin E associated events during G1/S transition (Rattus norvegicus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
SCF(Skp2)-mediated degradation of p27/p21 (Rattus norvegicus)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Rattus norvegicus)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
S Phase (Rattus norvegicus)
Cyclin A:Cdk2-associated events at S phase entry (Rattus norvegicus)
Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
SCF(Skp2)-mediated degradation of p27/p21 (Rattus norvegicus)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Rattus norvegicus)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cellular responses to external stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular Senescence (Rattus norvegicus)
DNA Damage/Telomere Stress Induced Senescence (Rattus norvegicus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Senescence-Associated Secretory Phenotype (SASP) (Rattus norvegicus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Transcription of Cell Cycle Genes (Rattus norvegicus)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Rattus norvegicus)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Rattus norvegicus)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Rattus norvegicus)
Participants
members
Cdkn1a [nucleoplasm] (Rattus norvegicus)
Cdkn1b [nucleoplasm] (Rattus norvegicus)
candidates
Cdkn1c [nucleoplasm] (Rattus norvegicus)
Participant Of
input
Inactivation of Cyclin A:Cdk2 complexes by p27/p21
Inactivation of Cyclin E:Cdk2 complexes by p27/p21
hasComponent
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm]
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm]
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm]
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm]
Inferred From
CDKN1A,CDKN1B [nucleoplasm] (Homo sapiens)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Homo sapiens)
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