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About
What is Reactome ?
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PI3K-regulatory subunit [cytosol]
Stable Identifier
R-RNO-74688
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
Tie2 Signaling (Rattus norvegicus)
Interaction of Tie2 and p85 of PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p85 bound to Tie2 [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
TCR signaling (Rattus norvegicus)
Downstream TCR signaling (Rattus norvegicus)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Rattus norvegicus)
PI3K bound to TRAT [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Recruitment of PI3K to plasma membrane (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K bound to TRAT [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
DAP12 interactions (Rattus norvegicus)
DAP12 signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p85 regulatory unit of PI3K binds p-6Y-SYK (Rattus norvegicus)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
Role of LAT2/NTAL/LAB on calcium mobilization (Rattus norvegicus)
PI3K associates with phosphorylated GAB2 (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Phosphorylation of PIP2 to PIP3 by PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
Role of phospholipids in phagocytosis (Rattus norvegicus)
PI3K binds to p-6Y-SYK (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K:p-6Y-SYK [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K:p-6Y-SYK [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K bound to TRAT [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K bound to TRAT [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS:GTP binds PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p21 RAS:GTP:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
Active ALK recruits PI3K (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)
Active ALK:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by Insulin receptor (Rattus norvegicus)
Insulin receptor signalling cascade (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
PI3K-containing complexes [cytosol] (Rattus norvegicus)
Activated FGFR bound to PI3K [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by LTK (Rattus norvegicus)
Active LTK receptor binds PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-5Y LTK dimer:ALKAL1,2:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
PI3K/AKT activation (Rattus norvegicus)
Active IRS recruits PI3K to the plasma membrane and activates it (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K produces PIP3 and other phosphatidyl inositides (Rattus norvegicus)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
PI3-kinase binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by SCF-KIT (Rattus norvegicus)
Synthesis of PIP3 from PIP2 by PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Rattus norvegicus)
IGF1R signaling cascade (Rattus norvegicus)
IRS-related events triggered by IGF1R (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
PI3K-containing complexes [cytosol] (Rattus norvegicus)
Activated FGFR bound to PI3K [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] (Rattus norvegicus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
p-AXL binds PI3K (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] (Rattus norvegicus)
PI3K [cytosol] (Rattus norvegicus)
PI3K-regulatory subunit [cytosol] (Rattus norvegicus)
Participants
members
Pik3r1 [cytosol]
(Rattus norvegicus)
Pik3r2 [cytosol]
(Rattus norvegicus)
Participates
as a component of
PI3K [cytosol] (Rattus norvegicus)
Inferred From
PI3K-regulatory subunit [cytosol]
(Homo sapiens)
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