Reactome | Rpl9 [cytosol]

Rpl9 [cytosol]

Stable Identifier

R-RNO-72492-2

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

RPL9, P17077

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
- rRNA processing (Rattus norvegicus)
  - rRNA processing in the nucleus and cytosol (Rattus norvegicus)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Rattus norvegicus)
      - 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)

Metabolism of proteins (Rattus norvegicus)

- Translation (Rattus norvegicus)
  - Eukaryotic Translation Initiation (Rattus norvegicus)
    - Cap-dependent Translation Initiation (Rattus norvegicus)
      - Formation of a pool of free 40S subunits (Rattus norvegicus)
        
        Release of 40S and 60S subunits from the 80S ribosome (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
      - GTP hydrolysis and joining of the 60S ribosomal subunit (Rattus norvegicus)
        
        The 60S subunit joins the translation initiation complex (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
        
        80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
        
        eIF5B:GTP is hydrolyzed and released (Rattus norvegicus)
        
        80S:Met-tRNAi:mRNA [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
        
        80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
    - L13a-mediated translational silencing of Ceruloplasmin expression (Rattus norvegicus)
      - Dissociation of L13a from the 60s ribosomal subunit (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
        
        60s ribosomal complex lacking L13a subunit [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
  - SRP-dependent cotranslational protein targeting to membrane (Rattus norvegicus)
    - Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Rattus norvegicus)
      - SRP:polypeptide+signal:ribosome [cytosol] (Rattus norvegicus)
        
        ribosome:mRNA:polypeptide+signal [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)
      - ribosome:mRNA:polypeptide+signal [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL9 [cytosol] (Rattus norvegicus)
        
        Rpl9 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P17077

Gene Names

Rpl9

Reference Genes

BioGPS Gene:29257 Rpl9

ENSEMBL:ENSRNOG00000026716

ENSEMBL:ENSRNOG00000026716.6 Rpl9

ENSEMBL:ENSRNOG00000028449

ENSEMBL:ENSRNOG00000028449.5 Rpl9

ENSEMBL:ENSRNOG00000030476

ENSEMBL:ENSRNOG00000030476.6 Rpl9

ENSEMBL:ENSRNOG00055017984

ENSEMBL:ENSRNOG00060015961

ENSEMBL:ENSRNOG00065013441

KEGG Gene (Rattus norvegicus):100360449 Rpl9

KEGG Gene (Rattus norvegicus):100364457 Rpl9

KEGG Gene (Rattus norvegicus):29257 Rpl9

Monarch:29257 Rpl9

NCBI Gene:29257 Rpl9

UCSC:P17077 Rpl9

Reference Transcript

Other Identifiers

103692519

10719210

10726650

10754136

10772718

10776256

10822520

10834475

10873870

10875768

10901711

10932126

1371301_at

17630004

17689883

17760216

29257

5638762

5641619

5709184

5720374

5838336

5843375

5967746

6039622

6074352

6090176

6118991

6191487

6195005

6200934

6216152

6229418

6303296

6362248

6371629

6430770

6447794

6453825

6458388

6491790

6501986

6502241

6519460

6582013

GE1134003

GO:0003723

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0019843

GO:0043226

ILMN_1362251

PH_rn_0024028

PH_rn_0024029

X51706cds_at

X51706cds_g_at

rc_AI235497_s_at

Participates

as a member of

Homologues of RPL9 [cytosol] (Rattus norvegicus)

Inferred From

RPL9 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_002729193.1, XP_002725578.1, XP_003753735.1, NP_001007599.3, XP_003748822.1

Ensembl

ENSRNOG00000026716, ENSRNOT00000042201, ENSRNOP00000032635, ENSRNOG00000030476, ENSRNOT00000038927, ENSRNOT00000052231, ENSRNOP00000069650, ENSRNOG00000028449, ENSRNOP00000041817

PRO

P17077

RGD

62049

PDB

7QGG

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