Reactome | Ell2 [nucleoplasm]

Ell2 [nucleoplasm]

Stable Identifier

R-RNO-6807506

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

ELL2, A0A8I6A5G5

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)
        
        Ell2 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I6A5G5

Gene Names

Ell2

Reference Genes

BioGPS Gene:309918 Ell2

ENSEMBL:ENSRNOG00000027089

ENSEMBL:ENSRNOG00000027089.7 Ell2

KEGG Gene (Rattus norvegicus):309918 Ell2

Monarch:309918 Ell2

NCBI Gene:309918 Ell2

Reference Transcript

Other Identifiers

10812201

1389680_at

17734860

309918

5629586

5697158

5777876

5831549

5910060

5965868

6000295

6076405

6123338

6174314

6375027

6476619

6505817

6526793

6626373

6714352

6741609

A_44_P470961

GE1164309

GE1204178

GO:0005634

GO:0005654

GO:0006351

GO:0006368

GO:0008023

GO:0016073

GO:0042795

GO:0043226

ILMN_1363228

PH_rn_0016704

rc_AI043849_at

Participates

as a member of

ELL,ELL2,ELL3 [nucleoplasm] (Rattus norvegicus)

Inferred From

ELL2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_001054852.2, XP_008758825.1

Ensembl

ENSRNOG00000027089, ENSRNOP00000087256, ENSRNOT00000108554

RGD

1309296

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