Reactome | phospho-Il4r [plasma membrane]

phospho-Il4r [plasma membrane]

Stable Identifier

R-RNO-6786087

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

p-Y-IL4R, Q63257

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Signaling by Interleukins (Rattus norvegicus)
    - Interleukin-4 and Interleukin-13 signaling (Rattus norvegicus)
      - IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - JAK1 phosphorylates STAT3,STAT6 (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:p-Y705-STAT3,p-Y641-STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - STAT1,STAT3,STAT6 bind IL13:IL13R type II (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - STAT3,STAT6 bind p-Y-IL4R (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - p-Y-STATs dissociate (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Rattus norvegicus)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
      - p-Y705-STAT3,p-Y641-STAT6 dissociate (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:p-Y705-STAT3,p-Y641-STAT6 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] (Rattus norvegicus)
        
        IL4:p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-Y-IL4R:JAK2 [plasma membrane] (Rattus norvegicus)
        
        phospho-Il4r [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q63257

Gene Names

Il4r

Reference Genes

BioGPS Gene:25084 Il4r

ENSEMBL:ENSRNOG00000015441

ENSEMBL:ENSRNOG00000015441.8 Il4r

ENSEMBL:ENSRNOG00055030626

ENSEMBL:ENSRNOG00060032143

KEGG Gene (Rattus norvegicus):25084 Il4r

Monarch:25084 Il4r

NCBI Gene:25084 Il4r

UCSC:Q63257 Il4r

Reference Transcript

Other Identifiers

10710782

1368134_a_at

17620538

25084

5666245

5733266

5806516

5883412

5896077

5913034

5922048

5927108

6024861

6034241

6037504

6157468

6249773

6580120

6638432

6707183

6744300

A_44_P337300

A_64_P089531

GE13053

GO:0002532

GO:0004896

GO:0005515

GO:0006954

GO:0016020

GO:0023052

GO:0060089

ILMN_1372125

PH_rn_0015251

X69903_at

rc_AI010262_at

Participates

as a component of

Other forms of this molecule

Il4r [plasma membrane]

Inferred From

p-Y-IL4R [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_008758086.1, XP_006230277.1, XP_017444292.1, XP_017444293.1, XP_006230278.1, XP_008758085.1, NP_596871.2

Ensembl

ENSRNOT00000020994, ENSRNOP00000020994, ENSRNOG00000015441

PRO

Q63257

RGD

2899

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