Reactome | Areg [ER to Golgi transport vesicle membrane]

Areg [ER to Golgi transport vesicle membrane]

Stable Identifier

R-RNO-5689771

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

ER to Golgi transport vesicle membrane

Synonyms

AREG precursor, P24338

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPII-mediated vesicle transport (Rattus norvegicus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CSNK1D phosphorylates SEC23 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Nucleotide exchange on RAB1 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Vesicle budding (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - ER to Golgi Anterograde Transport (Rattus norvegicus)
    - COPII-mediated vesicle transport (Rattus norvegicus)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
      - COPII coat binds TRAPPCII and RAB1:GDP (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
      - CSNK1D phosphorylates SEC23 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
      - Nucleotide exchange on RAB1 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
      - Vesicle budding (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        CNIH1:TFGA,AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        Areg [ER to Golgi transport vesicle membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P24338

Gene Names

Areg

Reference Genes

BioGPS Gene:29183 Areg

ENSEMBL:ENSRNOG00000002754

ENSEMBL:ENSRNOG00055006387

ENSEMBL:ENSRNOG00060017437

ENSEMBL:ENSRNOG00065018693

KEGG:rno:29183 Areg

Monarch:29183 Areg

NCBI Gene:29183 Areg

UCSC:P24338 Areg

Reference Transcript

RefSeq:NM_017123.1 Areg

Other Identifiers

10775866

1369871_at

17693425

29183

6047246

6259282

6322352

6408633

6425245

6487267

6530692

6546529

A_42_P791677

GE20356

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0007173

GO:0007186

GO:0008284

GO:0009986

GO:0022414

GO:0023052

GO:0030297

GO:0032355

GO:0036211

GO:0038134

GO:0043226

GO:0048018

GO:0048856

GO:0050731

GO:0060598

GO:0060744

GO:0060749

GO:0060750

GO:0098772

ILMN_1363074

PH_rn_0015046

X55183_at

Participates

as a member of

TFGA, AREG precursors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)

Other forms of this molecule

Areg [clathrin-coated endocytic vesicle membrane]

Areg [endoplasmic reticulum-Golgi intermediate compartment membrane]

Areg [endoplasmic reticulum membrane]

Areg [extracellular region]

Inferred From

AREG precursor [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_058819.1

ENSEMBL

ENSRNOP00000003703, ENSRNOT00000003703

PRO

P24338

GlyGen

P24338

RGD

2149

Cite Us!