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F8 [endoplasmic reticulum lumen]
Stable Identifier
R-RNO-5689449
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum lumen
Synonyms
F8 precursor, D3ZEB1
Locations in the PathwayBrowser
Expand all
Hemostasis (Rattus norvegicus)
Formation of Fibrin Clot (Clotting Cascade) (Rattus norvegicus)
Intrinsic Pathway of Fibrin Clot Formation (Rattus norvegicus)
FVIII is secreted (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Transport to the Golgi and subsequent modification (Rattus norvegicus)
ER to Golgi Anterograde Transport (Rattus norvegicus)
COPII-mediated vesicle transport (Rattus norvegicus)
Inner coat assembly and cargo binding (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Loss of SAR1B GTPase (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Vesicle budding (Rattus norvegicus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Cargo concentration in the ER (Rattus norvegicus)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Inner coat assembly and cargo binding (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
ER to Golgi Anterograde Transport (Rattus norvegicus)
COPII-mediated vesicle transport (Rattus norvegicus)
Inner coat assembly and cargo binding (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Loss of SAR1B GTPase (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Vesicle budding (Rattus norvegicus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Cargo concentration in the ER (Rattus norvegicus)
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
Inner coat assembly and cargo binding (Rattus norvegicus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
COPII cargo:receptors [endoplasmic reticulum membrane] (Rattus norvegicus)
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
F8 [endoplasmic reticulum lumen] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZEB1
Gene Names
F8
Reference Genes
BioGPS Gene:302470 F8
ENSEMBL:ENSRNOG00000031197
Monarch:302470 F8
NCBI Gene:302470 F8
UCSC:D3ZEB1 F8
Reference Transcript
RefSeq:NM_183331.2 F8
Other Identifiers
10800038
1380190_at
1380367_at
1382194_at
1395015_at
1395916_at
1396181_at
17721315
302470
5647390
5659223
5661114
5694102
5705127
5707144
5720970
5729005
5814124
5823923
5828649
5846618
5857873
5885476
5917742
5934716
5959906
5963818
5972659
6006381
6045915
6089736
6115704
6123930
6132513
6133518
6146326
6153048
6161399
6182905
6193128
6207162
6231461
6247403
6249266
6255430
6258792
6258969
6296549
6308684
6366714
6368104
6368329
6442559
6450091
6451701
6479765
6495947
6529095
6571549
6585775
6641811
6713645
6728029
6734642
6737400
6742748
A_64_P110759
GE1118061
GE14872
GE17897
GO:0005507
GO:0016491
ILMN_1359990
rc_AI176907_at
rc_AI234173_at
Participates
as an input of
Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Rattus norvegicus)
FVIII is secreted (Rattus norvegicus)
as a component of
LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum membrane] (Rattus norvegicus)
Other forms of this molecule
F8 [Golgi lumen]
F8 [Golgi lumen]
F8 [extracellular region]
F8 [extracellular region]
F8 [extracellular region]
F8 [extracellular region]
F8 [endoplasmic reticulum-Golgi intermediate compartment membrane]
F8 [COPII-coated ER to Golgi transport vesicle]
F8 [extracellular region]
F8 [platelet alpha granule lumen]
F8 [extracellular region]
F8 [extracellular region]
F8 [extracellular region]
F8 [extracellular region]
F8 [extracellular region]
F8 [plasma membrane]
F8 [plasma membrane]
F8 [plasma membrane]
Inferred From
glycosylated FV, FVIII precursor [endoplasmic reticulum lumen]
(Homo sapiens)
F8 precursor [endoplasmic reticulum lumen]
(Homo sapiens)
Cross References
RefSeq
NP_899160.2
ENSEMBL
ENSRNOG00000031197
,
ENSRNOP00000050792
,
ENSRNOT00000045926
RGD
727845
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