Reactome | Xrcc3 [nucleoplasm]

Xrcc3 [nucleoplasm]

Stable Identifier

R-RNO-5685303

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

XRCC3, D4A5N4

Locations in the PathwayBrowser

Expand all

DNA Repair (Rattus norvegicus)

- DNA Double-Strand Break Repair (Rattus norvegicus)
  - Homology Directed Repair (Rattus norvegicus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Rattus norvegicus)
      - HDR through Homologous Recombination (HRR) (Rattus norvegicus)
        
        D-loop extension by DNA polymerases (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Homologous DNA Pairing and Strand Exchange (Rattus norvegicus)
        
        CX3 complex binds D-loop structures (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex formation (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Resolution of D-Loop Structures (Rattus norvegicus)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Rattus norvegicus)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Rattus norvegicus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        MUS81:EME1,EME2 cleaves D-loop (Rattus norvegicus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        CX3 complex [nucleoplasm] (Rattus norvegicus)
        
        Xrcc3 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4A5N4

Gene Names

Xrcc3

Reference Genes

BioGPS Gene:102551085 Xrcc3

ENSEMBL:ENSRNOG00000012141

ENSEMBL:ENSRNOG00000012141.4 Xrcc3

KEGG Gene (Rattus norvegicus):102551085 Xrcc3

Monarch:102551085 Xrcc3

NCBI Gene:102551085 Xrcc3

UCSC:D4A5N4 Xrcc3

Reference Transcript

Other Identifiers

102551085

10892279

1389356_at

17824462

5689000

5726244

5819425

6158034

6162466

6224284

6481509

6604012

6628319

GE16661

GO:0000278

GO:0000400

GO:0000722

GO:0000724

GO:0003677

GO:0003824

GO:0005524

GO:0005634

GO:0005654

GO:0005657

GO:0005694

GO:0005737

GO:0005739

GO:0005829

GO:0006281

GO:0006310

GO:0007010

GO:0007059

GO:0008821

GO:0010824

GO:0016787

GO:0023052

GO:0032200

GO:0033065

GO:0036297

GO:0043226

GO:0048471

GO:0071140

GO:0090267

GO:0090656

GO:0090737

GO:0140014

GO:0140097

GO:0140299

GO:0140657

GO:0140664

PH_rn_0001002

rc_AA957570_at

Participates

as an input of

CX3 complex formation (Rattus norvegicus)

as a component of

CX3 complex [nucleoplasm] (Rattus norvegicus)

Inferred From

XRCC3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_008774546.1, XP_008763204.1, XP_008774547.1, XP_006240712.1, XP_008774548.1, XP_006240711.1

Ensembl

ENSRNOP00000016208, ENSRNOT00000016208, ENSRNOG00000012141

RGD

1306849

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