Reactome | KIF24 [cytosol]

KIF24 [cytosol]

Stable Identifier

R-RNO-5626651

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

D4A7G8

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Rattus norvegicus)

- Cilium Assembly (Rattus norvegicus)
  - Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - C2CD3 binds the mother centriole (Rattus norvegicus)
      - mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - MARK4 binds ODF2 in the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - Recruitment of transition zone proteins (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
    - The distal appendage proteins recruit TTBK2 (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        KIF24 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4A7G8

Reference Genes

BioGPS Gene:313170

ENSEMBL:ENSRNOG00000012735

ENSEMBL:ENSRNOG00000012735.7

KEGG Gene (Rattus norvegicus):313170

Monarch:313170

NCBI Gene:313170

UCSC:D4A7G8

Reference Transcript

Other Identifiers

10876131

17806581

313170

5622890

5623956

5666718

5689627

5723458

5761516

5841148

5845336

5895693

5904220

5938702

5948997

5953913

5958143

6063816

6074110

6118346

6137063

6140659

6173486

6282314

6323292

6359770

6366629

6391170

6546546

6629886

6651772

6668182

6739680

A_44_P356615

A_64_P111410

GO:0003774

GO:0003777

GO:0005515

GO:0005524

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0007010

GO:0007018

GO:0007019

GO:0008017

GO:0008092

GO:0032991

GO:0042802

GO:0043226

GO:0044782

GO:0060271

GO:0140657

GO:1902018

ILMN_1358208

PH_rn_0001392

Participates

as a component of

Inferred From

KIF24 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006225309.1, XP_017449203.1, XP_017458478.1, XP_017449202.1, XP_017449204.1, XP_006238175.1, XP_017458479.1, XP_017458480.1

Ensembl

ENSRNOT00000035541, ENSRNOP00000035304, ENSRNOG00000012735

RGD

1307723

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