Reactome | Iqcb1 [cytosol]

Iqcb1 [cytosol]

Stable Identifier

R-RNO-5626648

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

IQCB1, A0A8I5ZLP5

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Rattus norvegicus)

- Cilium Assembly (Rattus norvegicus)
  - Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - C2CD3 binds the mother centriole (Rattus norvegicus)
      - mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - MARK4 binds ODF2 in the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - Recruitment of transition zone proteins (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
    - The distal appendage proteins recruit TTBK2 (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Iqcb1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZLP5

Gene Names

Iqcb1

Reference Genes

BioGPS Gene:303915 Iqcb1

ENSEMBL:ENSRNOG00000038868

ENSEMBL:ENSRNOG00000038868.4 Iqcb1

Monarch:303915 Iqcb1

NCBI Gene:303915 Iqcb1

Reference Transcript

Other Identifiers

10754337

1390162_at

17669270

303915

5666361

5757939

5800130

5821192

5929364

5942093

6056861

6076125

6085536

6277020

6277107

6342047

6422144

6451355

6587994

6688610

6719556

A_42_P571235

A_44_P377910

GE1180044

GE14870

GO:0001750

GO:0005515

GO:0005516

GO:0005634

GO:0005654

GO:0005813

GO:0005815

GO:0005856

GO:0005929

GO:0015630

GO:0019899

GO:0030154

GO:0032391

GO:0043226

GO:0044782

GO:0045171

GO:0045494

GO:0048496

GO:0048856

GO:0060271

GO:0072686

ILMN_1367093

PH_rn_0008064

rc_AI234142_at

Participates

as a component of

Inferred From

IQCB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006248459.1, XP_006248458.1, XP_017453487.1, XP_006248457.1, XP_008766952.1

Ensembl

ENSRNOT00000100750, ENSRNOP00000078884, ENSRNOG00000038868

RGD

1310069

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