Reactome | Mrps18a [mitochondrial inner membrane]

Mrps18a [mitochondrial inner membrane]

Stable Identifier

R-RNO-5368200

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

mitochondrial inner membrane

Synonyms

MRPS18A, Q6PDU2

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Translation (Rattus norvegicus)
  - Mitochondrial translation (Rattus norvegicus)
    - Mitochondrial translation elongation (Rattus norvegicus)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Rattus norvegicus)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
    - Mitochondrial translation termination (Rattus norvegicus)
      - 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Rattus norvegicus)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
      - MRRF binds 55S ribosome:mRNA:tRNA (Rattus norvegicus)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Rattus norvegicus)
        
        55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Rattus norvegicus)
        
        55S ribosome [mitochondrial inner membrane] (Rattus norvegicus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Rattus norvegicus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)
        
        Mrps18a [mitochondrial inner membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q6PDU2

Gene Names

Mrps18a

Reference Genes

BioGPS Gene:301249 Mrps18a

ENSEMBL:ENSRNOG00000019511

ENSEMBL:ENSRNOG00000019511.6 Mrps18a

KEGG Gene (Rattus norvegicus):301249 Mrps18a

Monarch:301249 Mrps18a

NCBI Gene:301249 Mrps18a

UCSC:Q6PDU2 Mrps18a

Reference Transcript

RefSeq:NM_198756.2 Mrps18a

Other Identifiers

10926570

1371591_at

17862923

301249

5678769

5797331

5971400

6090627

6102224

6123929

6235691

6527481

6670974

A_42_P619308

GE17006

GO:0003735

GO:0005198

GO:0005739

GO:0005762

GO:0005763

GO:0005840

GO:0006412

GO:0043226

ILMN_1369755

PH_rn_0010768

rc_AA858667_at

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Rattus norvegicus)

Inferred From

MRPS18A [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_942051.1

Ensembl

ENSRNOT00000026499, ENSRNOP00000026499, ENSRNOG00000019511

RGD

735229

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