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TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
Stable Identifier
R-RNO-5362479
Type
Complex
Species
Rattus norvegicus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Rattus norvegicus)
TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 (Rattus norvegicus)
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Rattus norvegicus)
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Rattus norvegicus)
x 2
Tank [cytosol]
(Rattus norvegicus)
Participates
as an output of
TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 (Rattus norvegicus)
as an input of
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Rattus norvegicus)
Inferred From
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Homo sapiens)
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