Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-T507,S645,S664-PRKCD [cytosol]
Stable Identifier
R-RNO-5218734
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P09215
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CLEC7A (Dectin-1) signaling (Rattus norvegicus)
PKC-delta is activated (Rattus norvegicus)
DAGs:p-T507,S645,S664-PRKCD [plasma membrane] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
PKC-delta translocates to plasma membrane (Rattus norvegicus)
DAGs:p-T507,S645,S664-PRKCD [plasma membrane] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated cell proliferation (Rattus norvegicus)
DAG and Ca+2 bind to PKC and tether it to membrane (Rattus norvegicus)
DAG:active PKC:Ca+2 [plasma membrane] (Rattus norvegicus)
p-PKC [cytosol] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
p-PKC [cytosol] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
PKC autophosphorylates (Rattus norvegicus)
p-PKC [cytosol] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
PKC phosphorylates sphingosine kinase 1 (Rattus norvegicus)
DAG:active PKC:Ca+2 [plasma membrane] (Rattus norvegicus)
p-PKC [cytosol] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
p-PKC [cytosol] (Rattus norvegicus)
phospho-p-T507,S645,S664-PRKCD [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P09215 Prkcd
Gene Names
Prkcd, Pkcd
Chain
chain:1-673, chain:1-327, chain:328-673
Reference Genes
BioGPS Gene:170538 Prkcd
KEGG Gene (Rattus norvegicus):170538 Prkcd
Monarch:170538 Prkcd
NCBI Gene:170538 Prkcd
UCSC:P09215 Prkcd
Reference Transcript
RefSeq:NM_133307.1 Prkcd
Participates
as a member of
p-PKC [cytosol] (Rattus norvegicus)
as an input of
PKC-delta translocates to plasma membrane (Rattus norvegicus)
as a component of
DAGs:p-T507,S645,S664-PRKCD [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
PRKCD(1-676) [nucleoplasm]
PRKCD(330-676) [extracellular region]
PRKCD(1-329) [extracellular region]
PRKCD(1-329) [azurophil granule lumen]
PRKCD(330-676) [azurophil granule lumen]
phospho-p-T507-PRKCD [cytosol]
phospho-p-T507,S645,S664-PRKCD(1-676) [plasma membrane]
PRKCD(330-676) [cytosol]
PRKCD(1-329) [cytosol]
Prkcd [cytosol]
PRKCD [cytosol]
Inferred From
p-T507,S645,S664-PRKCD [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 507 (in Homo sapiens)
Coordinate
507
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 645 (in Homo sapiens)
Coordinate
645
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 664 (in Homo sapiens)
Coordinate
664
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_579841.1
PRO
P09215
RGD
67383
PDB
7KNJ
,
1BDY
,
7L92
,
7LF3
,
7KND
,
7LEO
,
7KO6
,
7LCB
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text