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Il6st [plasma membrane]
Stable Identifier
R-RNO-448453
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
IL6ST, P40190
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-12 family signaling (Rattus norvegicus)
Interleukin-27 signaling (Rattus norvegicus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Rattus norvegicus)
IL27:EBI3:IL27RA:p-JAK1:IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Rattus norvegicus)
IL6ST:(p-JAK1:p-JAK2:p-TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Rattus norvegicus)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL27:EBI3:IL27RA:p-JAK1:IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Rattus norvegicus)
IL6ST:(p-JAK1:p-JAK2:p-TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
Interleukin-35 Signalling (Rattus norvegicus)
IL35 binds IL-12RB2:IL6ST receptor (Rattus norvegicus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL35 binds IL6ST:IL6ST receptor (Rattus norvegicus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Rattus norvegicus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Rattus norvegicus)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:p-JAK1 [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:p-STAT1:p-STAT4 [plasma membrane] (Rattus norvegicus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:p-JAK1 [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Rattus norvegicus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:p-JAK1 [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Rattus norvegicus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL35:(IL6ST:p-JAK1:p-JAK2:p-TYK2) dimer [plasma membrane] (Rattus norvegicus)
IL6ST:p-JAK1:p-JAK2:p-TYK2 [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
STAT1 associates with IL6ST:IL6ST (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
p-STAT1 dissociates from IL6ST:IL6ST (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer:p-STAT1 [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
Interleukin-6 family signaling (Rattus norvegicus)
IL-6-type cytokine receptor ligand interactions (Rattus norvegicus)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
LIFR:JAKs bind gp130:JAKs:CNTFR (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
OSM,LIF,CTF1 receptor complex binds gp130 (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
LIF,OSM receptor complex:gp130 [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
gp130:JAKs bind CNTFR (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
Interleukin-6 signaling (Rattus norvegicus)
Assembly of hexameric IL-6 receptor (Rattus norvegicus)
IL6 receptor hexamer:JAKs [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6ST is tyrosine phosphorylated (Rattus norvegicus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
JAK activation (Rattus norvegicus)
IL6 receptor hexamer:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6 receptor hexamer:JAKs [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Il6st [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P40190
Gene Names
Il6st
Reference Genes
ENSEMBL:ENSRNOG00000013963
Participates
as a component of
IL6ST:p-JAK1:p-JAK2:p-TYK2 [plasma membrane] (Rattus norvegicus)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] (Rattus norvegicus)
IL6ST:p-JAK1 [plasma membrane] (Rattus norvegicus)
IL6ST:(p-JAK1:p-JAK2:p-TYK2) [plasma membrane] (Rattus norvegicus)
LIF,OSM receptor complex:gp130 [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6RB:Activated JAKs [plasma membrane] (Rattus norvegicus)
as an input of
OSM,LIF,CTF1 receptor complex binds gp130 (Rattus norvegicus)
Other forms of this molecule
phospho-Il6st [plasma membrane]
Il6st [extracellular region]
phospho-Il6st [plasma membrane]
Inferred From
IL6ST [plasma membrane]
(Homo sapiens)
Cross References
PRO
P40190
RGD
2903
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