Neurofascin binds Ankyrin-G

Stable Identifier
R-RNO-443773
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Neurofascin binds Ankyrin-G
The cytoplasmic domains of neurofascin contains a highly conserved sequence (F1315IGQY) that binds ankyrin. The membrane binding domain of ankyrin has two distinct binding sites for neurofascin and is proposed to form lateral complexes between ion channels and cell adhesion molecules as well as to couple these proteins to the spectrin based membrane skeleton.
Literature References
PubMed ID Title Journal Year
9804856 Structural requirements for association of neurofascin with ankyrin

Zhang, X, Bennett, V, Carpenter, S, Davis, JQ

J Biol Chem 1998
Participants
Input
Output
Orthologous Events
Neurofascin binds Ankyrin-G (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-12)
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