Reactome | LPAR1 [plasma membrane]

LPAR1 [plasma membrane]

Stable Identifier

R-RNO-419354

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P61794

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        LPAR1 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        LPAR1 [plasma membrane] (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        LPAR1 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        LPAR1 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Lysosphingolipid and LPA receptors (Rattus norvegicus)
        
        LPA-binding receptors bind LPA (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        LPAR1 [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        LPAR1 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P61794

Reference Genes

BioGPS Gene:116744

ENSEMBL:ENSRNOG00000013656

ENSEMBL:ENSRNOG00000013656.7

ENSEMBL:ENSRNOG00055018195

ENSEMBL:ENSRNOG00060011025

ENSEMBL:ENSRNOG00065016138

KEGG Gene (Rattus norvegicus):116744

Monarch:116744

NCBI Gene:116744

UCSC:P61794

Reference Transcript

Other Identifiers

10877069

116744

1370048_at

1374016_at

17807595

5632678

5771434

5812400

5959088

6010119

6072432

6379792

6593141

6673123

A_43_P12986

A_44_P496305

GE13320

GE17505

GE21312

GO:0004930

GO:0005768

GO:0005886

GO:0007010

GO:0007186

GO:0007193

GO:0008289

GO:0008360

GO:0009986

GO:0010977

GO:0016020

GO:0023052

GO:0030139

GO:0030154

GO:0030165

GO:0031410

GO:0032060

GO:0035025

GO:0035727

GO:0043123

GO:0043226

GO:0043410

GO:0044782

GO:0048856

GO:0048870

GO:0051496

GO:0060089

GO:0060326

GO:0070915

GO:0099004

GO:1902018

ILMN_1650631

PH_rn_0011649

rc_AA848831_at

rc_AI112149_at

Participates

as a member of

LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)

Inferred From

LPAR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_017448616.1, XP_006238259.1, XP_006238263.1, XP_006238257.1, XP_017448614.1, XP_017448617.1, XP_017448615.1, XP_006238262.1, NP_446388.1

ZINC - Substances

LPAR1_RAT

ZINC target

P61794

Ensembl

ENSRNOT00000044348, ENSRNOP00000043652, ENSRNOG00000013656

PRO

P61794

ZINC - Predictions - Purchasable

LPAR1_RAT

RGD

620563