Reactome | PDE2A [cytosol]

PDE2A [cytosol]

Stable Identifier

R-RNO-418499

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

Q01062

Locations in the PathwayBrowser

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Hemostasis (Rattus norvegicus)

- Platelet homeostasis (Rattus norvegicus)
  - Nitric oxide stimulates guanylate cyclase (Rattus norvegicus)
    - cGMP effects (Rattus norvegicus)
      - cGMP is degraded by PDEs (Rattus norvegicus)
        
        cGMP phosphodiesterases [cytosol] (Rattus norvegicus)
        
        Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Rattus norvegicus)
        
        PDE2A [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (s) signalling events (Rattus norvegicus)
      - cAMP degradation by Phosphodiesterases (Rattus norvegicus)
        
        cAMP PDEs [cytosol] (Rattus norvegicus)
        
        Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Rattus norvegicus)
        
        PDE2A [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q01062

Reference Genes

BioGPS Gene:81743

ENSEMBL:ENSRNOG00000019560

KEGG Gene (Rattus norvegicus):81743

Monarch:81743

NCBI Gene:81743

UCSC:Q01062

Reference Transcript

Participates

as a member of

Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Rattus norvegicus)

Inferred From

PDE2A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_112341.1, NP_001137319.1

ZINC - Substances

PDE2A_RAT

ZINC target

Q01062

PRO

Q01062

ZINC - Predictions - Purchasable

PDE2A_RAT

RGD

620965

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