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ARRB2 [cytosol]
Stable Identifier
R-RNO-416464
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P29067
Locations in the PathwayBrowser for interactor UniProt:P49187
Expand all
Hemostasis (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
Thrombin signalling through proteinase activated receptors (PARs) (Rattus norvegicus)
Activated PAR1 binds beta-arrestin-2 (Rattus norvegicus)
ARRB2 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
PCP/CE pathway (Rattus norvegicus)
WNT5A-dependent internalization of FZD4 (Rattus norvegicus)
WNT5A:FZD4 is endocytosed (Rattus norvegicus)
ARRB2 [cytosol] (Rattus norvegicus)
p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Rattus norvegicus)
ARRB2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P29067
Reference Genes
BioGPS Gene:25388
ENSEMBL:ENSRNOG00000019308
ENSEMBL:ENSRNOG00000019308
KEGG Gene (Rattus norvegicus):25388
Monarch:25388
NCBI Gene:25388
UCSC:P29067
Reference Transcript
RefSeq:NM_012911.1
Other Identifiers
10735205
1370265_at
17647752
17756756
2157
25388
5681608
5717651
5794024
5896837
5919323
6042245
6072139
6116464
6143136
6151309
6194558
6248256
6287221
6331317
6341351
6342882
6389479
6408748
6658514
A_44_P379214
AAA17551
AAA74460
AAC28617
AAH87578
AF051457
Arrb2
Arrb2-201
BC087578
ENSRNOG00000019308
ENSRNOP00000026207
ENSRNOT00000026207
EntrezGene:25388
EntrezGene:Arrb2
GE1240200
GE20051
GO:0000003
GO:0001664
GO:0001932
GO:0001933
GO:0001934
GO:0002031
GO:0002032
GO:0002092
GO:0002376
GO:0003674
GO:0005102
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005768
GO:0005886
GO:0005905
GO:0006259
GO:0006366
GO:0006464
GO:0006810
GO:0006897
GO:0006950
GO:0007005
GO:0007165
GO:0007179
GO:0007186
GO:0007267
GO:0007420
GO:0007628
GO:0008150
GO:0008219
GO:0008277
GO:0009056
GO:0009058
GO:0009968
GO:0010628
GO:0014069
GO:0015031
GO:0016020
GO:0016192
GO:0016323
GO:0016567
GO:0019899
GO:0019904
GO:0030139
GO:0030154
GO:0031397
GO:0031398
GO:0031410
GO:0031623
GO:0031625
GO:0031691
GO:0031692
GO:0031701
GO:0031702
GO:0031748
GO:0031762
GO:0031826
GO:0031859
GO:0032088
GO:0032226
GO:0032691
GO:0032695
GO:0032715
GO:0032720
GO:0032967
GO:0033138
GO:0034122
GO:0034260
GO:0034392
GO:0034641
GO:0040011
GO:0042699
GO:0042802
GO:0043154
GO:0043161
GO:0043197
GO:0043226
GO:0043231
GO:0043422
GO:0043524
GO:0044877
GO:0045211
GO:0045953
GO:0048856
GO:0048870
GO:0050731
GO:0050877
GO:0050965
GO:0051019
GO:0051897
GO:0051928
GO:0060090
GO:0060326
GO:0060765
GO:0070374
GO:0071889
GO:0090201
GO:1904037
GO:1990763
GO:2000573
GO:2000727
ILMN_1370634
IPR000698
IPR011021
IPR011022
IPR014752
IPR014753
IPR014756
IPR017864
M91590
M91590_at
M91590_g_at
NM_012911
NP_037043
PF00339
PF02752
PR00309
rc_AA964003_s_at
rc_AI013765_s_at
rc_AI136065_s_at
SM01017
U03627
UPI000012607D
Participant Of
hasMember
ARRB [cytosol]
CCP110,ARRB2,(ARRB1) [cytosol]
input
Activated PAR1 binds beta-arrestin-2
p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis
hasComponent
Activated PAR1:Beta-arrestin-2 [plasma membrane]
WNT5A:FZD4:p-DVL2:ARRB2 [plasma membrane]
output
WNT5A:FZD4 is endocytosed
hasCandidate
RAF/MAPK scaffolds [cytosol]
Other forms of this molecule
PolyUb-ARRB2 [cytosol]
Inferred From
ARRB2 [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_037043.1
PRO
P29067
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q00987 MDM2
11
SUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
MDM2 [plasma membrane]
(R-HSA-416843)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [cytosol]
(R-HSA-198644)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
0.688
4
UniProt:P29067
2
ARRB2 [cytosol]
(R-RNO-416464)
PolyUb-ARRB2 [cytosol]
(R-RNO-6783000)
0.591
3
UniProt:P31749 AKT1
13
p-T308,S473-AKT1 E17K [cytosol]
(R-HSA-2243935)
p-T308,S473-AKT1 E17K [nucleoplasm]
(R-HSA-2399994)
AKT1 E17K [cytosol]
(R-HSA-2219526)
p-S473-AKT1 E17K [plasma membrane]
(R-HSA-2243944)
AKT1 E17K [plasma membrane]
(R-HSA-1500573)
p-T308,S473-AKT1 [plasma membrane]
(R-HSA-199430)
p-Y315,Y326-AKT1 [cytosol]
(R-HSA-8848757)
p-T308-AKT1 [cytosol]
(R-HSA-198634)
p-T308,S473-AKT1 [nucleoplasm]
(R-HSA-198357)
AKT1 [cytosol]
(R-HSA-58252)
AKT1 [plasma membrane]
(R-HSA-199416)
p-S473-AKT1 [plasma membrane]
(R-HSA-377265)
p-T308,S473-AKT1 [cytosol]
(R-HSA-198356)
0.524
2
UniProt:P53667 LIMK1
3
p-T508-LIMK1 [cytosol]
(R-HSA-399816)
LIMK1 [cytosol]
(R-HSA-397785)
p-S,T508-LIMK1 [cytosol]
(R-HSA-419610)
0.524
2
UniProt:P49187
3
phospho-p-T221,Y223-MAPK10 [cytosol]
(R-RNO-450214)
MAPK10 [cytosol]
(R-RNO-450352)
phospho-p-T221,Y223-MAPK10 [nucleoplasm]
(R-RNO-450311)
0.508
3
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