Reactome | Htr5a [plasma membrane]

Htr5a [plasma membrane]

Stable Identifier

R-RNO-391007

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

HTR5A, P35364

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Rattus norvegicus)
        
        Htr5a [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Rattus norvegicus)
        
        Htr5a [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Amine ligand-binding receptors (Rattus norvegicus)
        
        Serotonin receptors (Rattus norvegicus)
        
        HTR1 and 5A receptors can bind serotonin (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Rattus norvegicus)
        
        Htr5a [plasma membrane] (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Rattus norvegicus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Rattus norvegicus)
        
        Htr5a [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P35364

Gene Names

Htr5a

Reference Genes

BioGPS Gene:25689 Htr5a

ENSEMBL:ENSRNOG00000007066

ENSEMBL:ENSRNOG00000007066.3 Htr5a

ENSEMBL:ENSRNOG00055005569

ENSEMBL:ENSRNOG00060023141

ENSEMBL:ENSRNOG00065004484

KEGG Gene (Rattus norvegicus):25689 Htr5a

Monarch:25689 Htr5a

NCBI Gene:25689 Htr5a

Reference Transcript

RefSeq:NM_013148.1 Htr5a

Other Identifiers

10859883

1369463_at

17788445

25689

5740907

5924272

5959304

6293072

6398596

6528486

6628876

6704667

A_43_P11737

A_64_P142011

GE20209

GE21680

GO:0004930

GO:0004993

GO:0005886

GO:0007186

GO:0007189

GO:0016020

GO:0023052

GO:0060089

L10072_at

PH_rn_0015762

Participates

as a member of

HTR1B,D,E,F,HTR5A [plasma membrane] (Rattus norvegicus)

Inferred From

HTR5A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_037280.1

ZINC - Substances

5HT5A_RAT

Ensembl

ENSRNOP00000009317, ENSRNOG00000007066, ENSRNOT00000009317

ZINC target

P35364

PRO

P35364

ZINC - Predictions - Purchasable

5HT5A_RAT

RGD

2851

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