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CDC42:GTP, RAC1:GTP [plasma membrane]
Stable Identifier
R-RNO-389778
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
Active RAC1/CDC42
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Costimulation by the CD28 family (Rattus norvegicus)
CD28 co-stimulation (Rattus norvegicus)
CD28 dependent Vav1 pathway (Rattus norvegicus)
Activation of PAKs by RAC1 and CDC42 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
Autophosphorylation of PAK1 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1 and CDC42 activate PAK1 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK6/MAPK4 signaling (Rattus norvegicus)
Activation of PAKs by RAC1 and CDC42 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate IQGAPs (Rattus norvegicus)
GTP-bound RAC1 and CDC42 bind IQGAPs (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
IQGAP1 binds CLIP1 and microtubules (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
IQGAPs bind CALM1 (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
IQGAPs bind F-actin, which is inhibited by calmodulin (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Rattus norvegicus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RHO GTPases activate PAKs (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1 and CDC42 activate PAK1 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1 and CDC42 activate PAK2 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
RAC1 and CDC42 activate PAK3 (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
Participants
members
CDC42:GTP [plasma membrane] (Rattus norvegicus)
Rac1:GTP [plasma membrane] (Rattus norvegicus)
Participant Of
hasComponent
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane]
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane]
RAC1,CDC42:GTP:IQGAP1 [plasma membrane]
RAC1,CDC42:GTP:IQGAPs [plasma membrane]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane]
input
Activation of PAKs by RAC1 and CDC42
GTP-bound RAC1 and CDC42 bind IQGAPs
RAC1 and CDC42 activate PAK1
RAC1 and CDC42 activate PAK2
RAC1 and CDC42 activate PAK3
output
Autophosphorylation of PAK1
Autophosphorylation of PAK1,2,3
Inferred From
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
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