Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-Dvl2 [cytosol]
Stable Identifier
R-RNO-3772398
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
pp-DVL2, D3ZB71
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases Activate Formins (Rattus norvegicus)
DAAM1 recruits GTP-bound RHOA (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL:DAAM1:RHOA:GTP [cytosol] (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL binds DAAM1 (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
PCP/CE pathway (Rattus norvegicus)
Asymmetric localization of PCP proteins (Rattus norvegicus)
SMURF1/2 are recruited to the DVL2:PARD6A complex (Rattus norvegicus)
PARD6A:pp-DVL2 [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
PARD6A:pp-DVL2:SMURF [plasma membrane] (Rattus norvegicus)
PARD6A:pp-DVL2 [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
SMURF1/2 ubiquitinates PRICKLE1 (Rattus norvegicus)
PARD6A:pp-DVL2:SMURF [plasma membrane] (Rattus norvegicus)
PARD6A:pp-DVL2 [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
DAAM1 recruits GTP-bound RHOA (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL:DAAM1:RHOA:GTP [cytosol] (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
DAAM1 recruits PFN1 (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL:DAAM1:PFN1 [cytosol] (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL binds DAAM1 (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL:DAAM1 [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL recruits RAC (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
pp-DVL:RAC:GTP [plasma membrane] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
TCF dependent signaling in response to WNT (Rattus norvegicus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Rattus norvegicus)
Beta-catenin is released from the destruction complex (Rattus norvegicus)
WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
DVL recruits GSK3beta:AXIN1 to the receptor complex (Rattus norvegicus)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Rattus norvegicus)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Rattus norvegicus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Rattus norvegicus)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
WNT mediated activation of DVL (Rattus norvegicus)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Rattus norvegicus)
ppDVL:PIP5K1B [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
ppDVL:PIP5K1B [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
phospho-Dvl2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZB71 Dvl2
Gene Names
Dvl2, rCG_34913
Reference Genes
BioGPS Gene:303251 Dvl2
ENSEMBL:ENSRNOG00000017915.7 Dvl2
KEGG Gene (Rattus norvegicus):303251 Dvl2
Monarch:303251 Dvl2
NCBI Gene:303251 Dvl2
UCSC:D3ZB71 Dvl2
Reference Transcript
RefSeq:NM_001172056.1 Dvl2
Other Identifiers
10735117
1389861_at
17647653
303251
5681346
5723440
5873487
5916871
5918536
5999345
6118530
6127018
6157760
6180002
6192769
6226059
6281142
6419768
6510171
6657132
6687023
6728043
A_44_P186407
GE1243422
GO:0001843
GO:0001934
GO:0001947
GO:0003007
GO:0003151
GO:0005109
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0007379
GO:0007507
GO:0008104
GO:0016055
GO:0016235
GO:0016328
GO:0016604
GO:0019901
GO:0019904
GO:0022007
GO:0023052
GO:0030136
GO:0030674
GO:0031267
GO:0031410
GO:0035282
GO:0035556
GO:0035567
GO:0036211
GO:0042127
GO:0042802
GO:0043226
GO:0043621
GO:0045177
GO:0045944
GO:0046330
GO:0048856
GO:0060029
GO:0060070
GO:0060071
GO:0060090
GO:0090103
GO:0090179
PH_rn_0017311
PH_rn_0021677
rc_AA956311_at
rc_AI103516_at
Participates
as a component of
PARD6A:pp-DVL2 [cytosol] (Rattus norvegicus)
as a member of
pp-DVL [cytosol] (Rattus norvegicus)
pp-DVL [cytosol] (Rattus norvegicus)
Other forms of this molecule
Dvl2 [cytosol]
phospho-Dvl2 [clathrin-coated endocytic vesicle]
Dvl2 [cytosol]
p-Dvl2 [cytosol]
Inferred From
pp-DVL2 [cytosol]
(Homo sapiens)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_001165527.1
Ensembl
ENSRNOG00000017915
,
ENSRNOP00000024348
,
ENSRNOT00000024348
RGD
1309725
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text