Reactome | Bdkrb2 [plasma membrane]

Bdkrb2 [plasma membrane]

Stable Identifier

R-RNO-374255

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

BDKRB2, P25023

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor [plasma membrane] (Rattus norvegicus)
        
        Bdkrb2 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor [plasma membrane] (Rattus norvegicus)
        
        Bdkrb2 [plasma membrane] (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor [plasma membrane] (Rattus norvegicus)
        
        Bdkrb2 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor [plasma membrane] (Rattus norvegicus)
        
        Bdkrb2 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Bradykinin receptors B1 and B2 bind to bradykinin (Rattus norvegicus)
        
        Bradykinin receptor [plasma membrane] (Rattus norvegicus)
        
        Bdkrb2 [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor:Bradykinin [plasma membrane] (Rattus norvegicus)
        
        Bradykinin receptor [plasma membrane] (Rattus norvegicus)
        
        Bdkrb2 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P25023

Gene Names

Bdkrb2

Reference Genes

BioGPS Gene:25245 Bdkrb2

ENSEMBL:ENSRNOG00000047300

ENSEMBL:ENSRNOG00065026514

KEGG Gene (Rattus norvegicus):25245 Bdkrb2

Monarch:25245 Bdkrb2

NCBI Gene:25245 Bdkrb2

UCSC:P25023 Bdkrb2

Reference Transcript

RefSeq:NM_173100.2 Bdkrb2

Participates

as a member of

Bradykinin receptor [plasma membrane] (Rattus norvegicus)

Inferred From

BDKRB2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_775123.2

ZINC - Substances

BKRB2_RAT

ZINC target

P25023

PRO

P25023

ZINC - Predictions - Purchasable

BKRB2_RAT

RGD

2201