Reactome | AGTR2 [plasma membrane]

AGTR2 [plasma membrane]

Stable Identifier

R-RNO-374130

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P35351

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        AGTR2:AGT(34-41) [plasma membrane] (Rattus norvegicus)
        
        AGTR2 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        AGTR2:AGT(34-41) [plasma membrane] (Rattus norvegicus)
        
        AGTR2 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        AGT(34-41) binds to AGTR2 (Rattus norvegicus)
        
        AGTR2 [plasma membrane] (Rattus norvegicus)
        
        AGTR2:AGT(34-41) [plasma membrane] (Rattus norvegicus)
        
        AGTR2 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P35351

Reference Genes

BioGPS Gene:24182

ENSEMBL:ENSRNOG00000050006

ENSEMBL:ENSRNOG00000050006.2

ENSEMBL:ENSRNOG00055025331

ENSEMBL:ENSRNOG00060019463

ENSEMBL:ENSRNOG00065009886

KEGG Gene (Rattus norvegicus):24182

Monarch:24182

NCBI Gene:24182

Reference Transcript

Other Identifiers

10931616

1369711_at

1398288_at

17869820

24182

5771723

5833908

6042935

6174745

6588550

A_42_P470283

A_44_P343615

A_64_P097458

D16840_s_at

D43778exon#3_s_at

GO:0001991

GO:0002033

GO:0002035

GO:0003013

GO:0003014

GO:0004930

GO:0004945

GO:0006351

GO:0006355

GO:0006954

GO:0007186

GO:0007199

GO:0010459

GO:0012501

GO:0016020

GO:0023052

GO:0035556

GO:0035566

GO:0035640

GO:0042981

GO:0045893

GO:0048856

GO:0050877

GO:0050886

GO:0051402

GO:0060089

GO:0072300

GO:0090190

GO:0097746

ILMN_1362684

PH_rn_0012305

U01908cds_s_at

Participates

as an input of

AGT(34-41) binds to AGTR2 (Rattus norvegicus)

as a component of

AGTR2:AGT(34-41) [plasma membrane] (Rattus norvegicus)

Inferred From

AGTR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_036626.1, XP_006257494.1

ZINC - Investigational

AGTR2_RAT

ZINC - World Drugs

AGTR2_RAT

ZINC - FDA approved

AGTR2_RAT

ZINC - Substances

AGTR2_RAT

Ensembl

ENSRNOG00000050006, ENSRNOT00000074269, ENSRNOP00000064709

ZINC target

P35351

PRO

P35351

ZINC - Predictions - Purchasable

AGTR2_RAT

RGD

2072

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