Reactome | CXCL4 homotetramer [extracellular region]

CXCL4 homotetramer [extracellular region]

Stable Identifier

R-RNO-373835

Type

Complex

Species

Rattus norvegicus

Compartment

extracellular region

Locations in the PathwayBrowser

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Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Chemokine receptors bind chemokines (Rattus norvegicus)
        
        Receptor CXCR2 binds ligands CXCL1 to 7 (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 4 Pf4 [extracellular region] (Rattus norvegicus)

Participates

as a member of

CXCR2 ligands [extracellular region] (Rattus norvegicus)

Inferred From

CXCL4 homotetramer [extracellular region] (Homo sapiens)

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