Reactome | Tas2r40 [plasma membrane]

Tas2r40 [plasma membrane]

Stable Identifier

R-RNO-3299608

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

TAS2R40, Q67ET2

Locations in the PathwayBrowser

Expand all

Sensory Perception (Rattus norvegicus)

- Sensory perception of taste (Rattus norvegicus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Rattus norvegicus)
    - Bitter compound binds bitter taste receptor (TAS2R) (Rattus norvegicus)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Rattus norvegicus)
        
        TAS2R (non-orphan) [plasma membrane] (Rattus norvegicus)
        
        Tas2r40 [plasma membrane] (Rattus norvegicus)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Rattus norvegicus)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Rattus norvegicus)
        
        TAS2R40:ligand [plasma membrane] (Rattus norvegicus)
        
        Tas2r40 [plasma membrane] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Rattus norvegicus)
        
        TAS2Rs [plasma membrane] (Rattus norvegicus)
        
        Tas2r40 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Rattus norvegicus)
        
        TAS2Rs [plasma membrane] (Rattus norvegicus)
        
        Tas2r40 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Rattus norvegicus)
      - T2Rs bind bitter-tasting compounds (Rattus norvegicus)
        
        TAS2Rs [plasma membrane] (Rattus norvegicus)
        
        Tas2r40 [plasma membrane] (Rattus norvegicus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Rattus norvegicus)
        
        TAS2Rs [plasma membrane] (Rattus norvegicus)
        
        Tas2r40 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q67ET2

Gene Names

Tas2r40

Reference Genes

BioGPS Gene:500101 Tas2r40

ENSEMBL:ENSRNOG00000028130

ENSEMBL:ENSRNOG00000028130.2 Tas2r40

ENSEMBL:ENSRNOG00055028864

ENSEMBL:ENSRNOG00060010799

KEGG Gene (Rattus norvegicus):500101 Tas2r40

Monarch:500101 Tas2r40

NCBI Gene:500101 Tas2r40

UCSC:Q67ET2 Tas2r40

Reference Transcript

RefSeq:NM_001025150.1 Tas2r40

Other Identifiers

10855006

17782980

500101

6532863

6647618

A_64_P106760

GO:0001580

GO:0004930

GO:0007186

GO:0016020

GO:0023052

GO:0033038

GO:0050877

GO:0050909

GO:0060089

ILMN_1370297

PH_rn_0004757

Participates

as a member of

as a component of

TAS2R40:ligand [plasma membrane] (Rattus norvegicus)

Inferred From

TAS2R40 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001020321.1

Ensembl

ENSRNOG00000028130, ENSRNOT00000037194, ENSRNOP00000033127

PRO

Q67ET2

RGD

1562314