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Rptor [cytosol]
Stable Identifier
R-RNO-3006727
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
RPTOR, D3ZDU2
Locations in the PathwayBrowser
Expand all
Autophagy (Rattus norvegicus)
Macroautophagy (Rattus norvegicus)
Active MTORC1 binds the ULK1 complex (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Rheb in the MTORC1 complex hydrolyses GTP (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to starvation (Rattus norvegicus)
Amino acids regulate mTORC1 (Rattus norvegicus)
RRAGA,B hydrolyzes GTP (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1 binds RHEB:GTP (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
PTEN Regulation (Rattus norvegicus)
Regulation of PTEN gene transcription (Rattus norvegicus)
MAF1 translocates to the nucleus (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1 phosphorylates MAF1 (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
MTOR signalling (Rattus norvegicus)
AKT1S1 (PRAS40) binds mTORC1 (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Formation of active mTORC1 complex (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1 phosphorylates AKT1S1 (Rattus norvegicus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1-mediated signalling (Rattus norvegicus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Rattus norvegicus)
mTORC1 [cytosol] (Rattus norvegicus)
Rptor [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZDU2
Gene Names
Rptor
Reference Genes
BioGPS Gene:287871 Rptor
ENSEMBL:ENSRNOG00000003821
ENSEMBL:ENSRNOG00000003821.7 Rptor
KEGG Gene (Rattus norvegicus):287871 Rptor
Monarch:287871 Rptor
NCBI Gene:287871 Rptor
Reference Transcript
RefSeq:NM_001134499.2 Rptor
Other Identifiers
10740050
1388646_at
17653183
287871
5709090
5731767
5804373
5901919
5935683
5962002
6026146
6034361
6044187
6052395
6067154
6087409
6126728
6128465
6136527
6149640
6156404
6208150
6222995
6234052
6257721
6274928
6276324
6311837
6314912
6332958
6421073
6448715
6459402
6462729
6506304
6513787
6557420
6593721
6610116
6663986
6706686
6713475
6727379
A_42_P651615
GE1280325
GE16142
GO:0000278
GO:0001558
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0006351
GO:0006355
GO:0006914
GO:0008361
GO:0010494
GO:0010507
GO:0010800
GO:0019901
GO:0023052
GO:0030291
GO:0030295
GO:0030307
GO:0030674
GO:0031267
GO:0031669
GO:0031929
GO:0031931
GO:0032008
GO:0033138
GO:0036211
GO:0038202
GO:0043226
GO:0044877
GO:0045945
GO:0060090
GO:0071230
GO:0071233
GO:0071333
GO:0071889
GO:0098772
GO:0140767
GO:1900087
ILMN_1361980
PH_rn_0006088
rc_AI058297_at
Participates
as a component of
mTORC1 [cytosol] (Rattus norvegicus)
Other forms of this molecule
Rptor [nucleoplasm]
phospho-Rptor [cytosol]
Inferred From
RPTOR [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001127971.2
Ensembl
ENSRNOG00000003821
,
ENSRNOP00000005337
,
ENSRNOT00000005337
RGD
1311784
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