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Tsc2 [cytosol]
Stable Identifier
R-RNO-2980548
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
TSC2, P49816
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
AKT phosphorylates TSC2, inhibiting it (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
Formation of TSC1:TSC2 complex (Rattus norvegicus)
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
AKT phosphorylates targets in the cytosol (Rattus norvegicus)
AKT phosphorylates TSC2, inhibiting it (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
MTOR signalling (Rattus norvegicus)
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
Inhibition of TSC complex formation by PKB (Rattus norvegicus)
Phosphorylation of TSC2 by PKB (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
Phosphorylation of complexed TSC2 by PKB (Rattus norvegicus)
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Rab regulation of trafficking (Rattus norvegicus)
TBC/RABGAPs (Rattus norvegicus)
TBC1D7 binds the TSC1-TSC2 complex (Rattus norvegicus)
TBC1D7:TSC1:TSC2 [cytosol] (Rattus norvegicus)
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Tsc2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P49816
Gene Names
Tsc2
Reference Genes
BioGPS Gene:24855 Tsc2
ENSEMBL:ENSRNOG00000011375
KEGG Gene (Rattus norvegicus):24855 Tsc2
Monarch:24855 Tsc2
NCBI Gene:24855 Tsc2
UCSC:P49816 Tsc2
Reference Transcript
RefSeq:NM_012680.3 Tsc2
RefSeq:XM_006245909.3 Tsc2
Participates
as an input of
Phosphorylation of TSC2 by PKB (Rattus norvegicus)
AKT phosphorylates TSC2, inhibiting it (Rattus norvegicus)
Formation of TSC1:TSC2 complex (Rattus norvegicus)
as a component of
TSC1:TSC2 [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Tsc2 [cytosol]
phospho-Tsc2 [cytosol]
phospho-Tsc2 [cytosol]
Inferred From
TSC2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006245971.2
,
NP_036812.2
PRO
P49816
RGD
3908
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