Dystroglycan binds Nrxn1

Stable Identifier
R-RNO-2426675
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
Synonyms
Dystroglycan binds Neurexin-1-alpha
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Dystroglycan binds Nrxn1
Dystroglycan binds specifically to a subset of neurexin LNS domains, in a tight interaction that requires the glycosylation of dystroglycan and is regulated by neurexin alternative splicing. Alpha-dystroglycan binds G domain-like sequences in neurexin-1-alpha (NRXN1) (Sugita et al. 2001).
Literature References
PubMed ID Title Journal Year
11470830 A stoichiometric complex of neurexins and dystroglycan in brain

Südhof, TC, Campbell, K, Saito, F, Satz, J, Tang, J, Sugita, S

J. Cell Biol. 2001
Participants
Orthologous Events
Authored
Reviewed
Created
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