AdoSeMet is converted to AdeSeHCys by MetTrans(2)

Stable Identifier
R-RNO-2408545
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
AdoSeMet is converted to AdeSeHCys by MetTrans(2)
In the cytosol of rat, a set of methyltransferases (MetTrans(2)) consisting of the proteins histamine-N-methyltransferase (Hnmt), glycine-N-methyltransferase (Gnmt), and nicotinamide-N-methyltransferase (Nnmt) remove a methyl group from adenosylselenomethionine (AdoSeMet) to leave adenosylselenohomocysteine (AdeSeHCys) (Kajander et al. 1991).
Literature References
PubMed ID Title Journal Year
1711890 Metabolism, cellular actions, and cytotoxicity of selenomethionine in cultured cells

Akerman, KK, Kärenlampi, SO, Martikainen, H, Harvima, RJ, Kajander, EO, Kantola, M, Eloranta, TO

Biol Trace Elem Res 1991
Participants
Input
Output
Catalyst Activity

selenol Se-methyltransferase activity of MetTrans(2) [cytosol]

Physical Entity
MetTrans(2) [cytosol] (Rattus norvegicus)
Activity
selenol Se-methyltransferase activity (GO:0098603)
Orthologous Events
AdoSeMet is converted to AdeSeHCys by MetTrans(1) (Homo sapiens)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
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