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Cd14 [endosome membrane]
Stable Identifier
R-RNO-2201284
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endosome membrane
Synonyms
GPIN-CD14(20-345), Q63691
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF(TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon (Rattus norvegicus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Rattus norvegicus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKE:IRF3/IRF7 [endosome membrane] (Rattus norvegicus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Rattus norvegicus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Cd14 [endosome membrane] (Rattus norvegicus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Rattus norvegicus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Cd14 [endosome membrane] (Rattus norvegicus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Rattus norvegicus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKE:IRF3/IRF7 [endosome membrane] (Rattus norvegicus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Rattus norvegicus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Cd14 [endosome membrane] (Rattus norvegicus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKKi [endosome membrane] (Rattus norvegicus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Cd14 [endosome membrane] (Rattus norvegicus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Rattus norvegicus)
Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Rattus norvegicus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Cd14 [endosome membrane] (Rattus norvegicus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Rattus norvegicus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)
Cd14 [endosome membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q63691
Gene Names
Cd14
Reference Genes
BioGPS Gene:60350 Cd14
ENSEMBL:ENSRNOG00000017819
ENSEMBL:ENSRNOG00000017819 Cd14
KEGG Gene (Rattus norvegicus):60350 Cd14
Monarch:60350 Cd14
NCBI Gene:60350 Cd14
UCSC:Q63691 Cd14
Reference Transcript
RefSeq:NM_021744.1 Cd14
Other Identifiers
10803991
1368490_at
17725716
5668393
5993747
60350
6072017
6214926
6442593
AF087943_s_at
AF087944mRNA_s_at
A_44_P469584
A_44_P519251
GE20789
GO:0001530
GO:0002237
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005794
GO:0005886
GO:0006810
GO:0006898
GO:0006950
GO:0006954
GO:0007165
GO:0007267
GO:0008150
GO:0008289
GO:0009408
GO:0009617
GO:0009897
GO:0009986
GO:0015031
GO:0016020
GO:0016192
GO:0031225
GO:0031362
GO:0031663
GO:0032026
GO:0032481
GO:0032496
GO:0032729
GO:0032757
GO:0032760
GO:0032991
GO:0034142
GO:0034612
GO:0043226
GO:0045087
GO:0045121
GO:0045471
GO:0045807
GO:0046696
GO:0050715
GO:0051602
GO:0070891
GO:0071219
GO:0071222
GO:0071223
GO:0071723
GO:0071726
GO:0071727
GO:1901224
ILMN_1352209
PH_rn_0012060
Participant Of
hasComponent
TLR4:LY96:LPS:CD14 [endosome membrane]
Other forms of this molecule
Cd14 [secretory granule membrane]
Cd14 [extracellular region]
Cd14 [plasma membrane]
Inferred From
GPIN-CD14(20-345) [endosome membrane] (Homo sapiens)
Modified Residues
Name
N-asparaginyl-glycosylphosphatidylinositolethanolamine at 345 (in Homo sapiens)
Coordinate
345
PsiMod Name
N-asparaginyl-glycosylphosphatidylinositolethanolamine [MOD:00167]
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N-asparaginyl-glycosylphosphatidylinositolethanolamine.
Cross References
RefSeq
NP_068512.1
Ensembl
ENSRNOT00000023977
,
ENSRNOG00000017819
,
ENSRNOP00000023977
PRO
Q63691
RGD
620588
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