Photolytic cleavage and thermal isomerization of 7-dehydrocholesterol

Stable Identifier
R-RNO-209770
Type
Reaction [omitted]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Photolytic cleavage and thermal isomerization of 7-dehydrocholesterol

The skin's exposure to UV rays from sunlight induces the photolytic cleavage of 7-dehydrocholesterol to previtamin D3. This is followed by thermal isomerization to form vitamin D3 (VD3, cholecalciferol) (Holick et al. 1977).

Literature References
PubMed ID Title Journal Year
194588 Photometabolism of 7-dehydrocholesterol to previtamin D3 in skin

Holick, MF, Frommer, JE, McNeill, SC, Richtand, NM, Henley, JW, Potts JT, Jr

Biochem Biophys Res Commun 1977
Participants
Orthologous Events
Authored
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