Dll1 binds Notch1

Stable Identifier
R-RNO-2050606
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
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Dll1 binds Notch1

By co-culturing two cell lines, one expressing recombinant rat Dll1 and the other expressing recombinant rat Notch1 (in the presence or absence of fringe enzymes), Yang et al. established that the fringe-modified Notch1 binds to Dll1 with higher affinity that Notch1 produced in the absence of fringe.

Literature References
PubMed ID Title Journal Year
15574878 Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1

Yang, LT, Nichols, JT, Yao, C, Manilay, JO, Robey, EA, Weinmaster, G

Mol Biol Cell 2005
Participants
Orthologous Events
Authored
Reviewed
Created
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